Caption: Figure 4 OCT reveals a choroidal neovascular membrane
with sub-retinal fluid
Submacular hemorrhage (SMH), may occur secondary to some ophthalmologic disorders such as choroidal neovascular membranes
(CNVM), ocular trauma, arterial macroaneurysms and pathological myopia.
To be able to identify patients with signs and symptoms of choroidal neovascular membrane
Patients with intermediate to large soft/ confluent drusen, with or without hyper- or hypo-pigmentation areas in the macular region, and no choroidal neovascular membrane
(CNV) or geographic atrophy, are considered to have early age-related maculopathy (ARM), (Figure 2).
The key finding in wet AMD is a choroidal neovascular membrane
Vitrectomy and removal of any choroidal neovascular membrane
Kramer, "Spectral-domain optical coherence tomographic features of choroidal neovascular membranes
in multifocal choroiditis and punctate inner choroidopathy," Graefe's Archive for Clinical and Experimental Ophthalmology, vol.
Decreased choriocapillaris perfusion following surgical excision of choroidal neovascular membranes
in age-related macular degeneration.
Peripapillary or juxtapapillary choroidal neovascular membranes
(CNVM) occur in patients due to a variety of conditions.
[19.] Derriman L, Marshall J, Moorman C & Downes SM (2008): The use of intravitreal bevacizumab to treat choroidal neovascular membranes
Caption: Figure 2 Conventional spectral-domain OCT b-scans: A) choroidal neovascular membranes
in wet AMD appear bright due to their reflective properties; B) geographic atrophy shows a typical thinning and/or loss of the outer retinal layers, RPE and choriocapillaris.
Basic fibroblast growth factor and vascular endothelial growth factor are present in epiretinal and choroidal neovascular membranes
. Am J Ophthalmol.