Keywords: Amniocentesis, chorionic villus
sampling, cordocenteses, prenatal genetic diagnostic testing
Transabdominal chorionic villus
sampling as an office procedure.
Feasibility and safety of transabdominal chorionic villus
The only definitive test involves chorionic villus
sampling and amniocentesis but that carries a risk of miscarriage.
Existing invasive diagnostic tests -- Chorionic villus
sampling (CVS) and amniocentesis, which use samples from the developing placenta, are still only 75-90 per cent accurate with a risk of miscarriage," he said.
KEY WORDS: b-thalassaemia, Prenatal diagnosis, Chorionic villus
It then covers complications such as recurrent spontaneous abortion, preeclampsia and eclampsia, postpartum hemorrhage, emergency care, blood group alloimmunizations, multiple gestations, prevention and management of preterm birth, placental disorders, prolonged pregnancy, cesarean and breech delivery, analgesia and anesthesia, and neonatal encephalopathy and cerebral palsy, ending with amniocentesis and chorionic villus
sampling procedures and fetal surgery.
It is often stated that more fetuses are lost due to such invasive procedures (amniocentesis and chorionic villus
sampling) than are identified as carrying a chromosomal abnormality.
Despite the decrease in HIV transmission with antiretroviral cover, procedures such as chorionic villus
sampling and cordocentesis should still be avoided in the HIV-infected woman as the risk of transmission to the fetus may be considerably higher.
(4) The Royal College of Obstetricians and Gynaecologists guideline on amniocentesis and chorionic villus
sampling advises that patients should be informed of an additional 1% risk of fetal loss following an amniocentesis, and a slightly higher risk following chorionic villus
All of these pregnant women are then offered the option of further, invasive tests including amniocentesis or chorionic villus
sampling, which have about a 1% risk of miscarriage.