chorionic gonadotropin


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gonadotropin

 [go´nah-do-tro″pin]
any hormone having a stimulating effect on the gonads. Two such hormones are secreted by the anterior pituitary gland: follicle-stimulating hormone and luteinizing hormone, both of which are active, but with differing effects, in the two sexes. Called also gonadotropic hormone.
chorionic gonadotropin (human chorionic gonadotropin (HCG) (hCG))
1. a glycopeptide hormone that is produced by cells of the fetal placenta and maintains the function of the corpus luteum during the first few weeks of pregnancy. It is thought to promote steroidogenesis in the fetoplacental unit and to stimulate fetal testicular secretion of testosterone. It can be detected by immunoassay in the maternal urine within days after fertilization; this provides the basis for the most commonly used pregnancy test.
2. the same principle obtained from the urine of pregnant women, used in treatment of certain cases of cryptorchidism and male hypogonadism, to induce ovulation and pregnancy in certain infertile, anovulatory women, and to increase the numbers of oocytes for patients attempting conception using assisted reproductive technologies such as gamete intrafallopian transfer or in vitro fertilization; administered intramuscularly. See also choriogonadotropin alfa.

cho·ri·on·ic go·nad·o·tro·pin (CG),

a glycoprotein with a carbohydrate fraction composed of d-galactose and hexosamine, extracted from the urine of pregnant women and produced by the placental trophoblastic cells; its most important role appears to be stimulation, during the first trimester, of ovarian secretion of the estrogen and progesterone required for the integrity of conceptus; it appears to play no significant role in the last two trimesters of pregnancy, as the estrogen and progesterone are then formed by the placenta. CG has luteinizing hormone activity and exerts its actions through luteinizing hormone receptors.

chorionic gonadotropin

Human chorionic gonadotrophin A hormone secreted by the anterior pituitary gland, which supports pregnancy Components α-hGH 14.5 kD; β-hGH 22.2 kD. See FSH, Gonadotropin, LH.
Chorionic gonadotropin levels–post conception
Weeks IU/L
1 wks 5-50
2 wks 40-1000
3 wks 100-4000
4 wks 800-10,000
5-6 wks 5000-100,000
8 wks 20,000-200,000
9-12 wks 10,000-200,000
2nd trimester 8,000-50,000
3rd trimester 6,000-50,000

cho·ri·on·ic go·nad·o·tro·pin

(kōr'ē-on'ik gō-nad'ō-trō'pin)
A glycoprotein with a carbohydrate fraction composed of d-galactose and hexosamine, produced by the placental trophoblastic cells; its most important role appears to be stimulation (during the first trimester) of ovarian secretion of the estrogen and progesterone required for the integrity of the conceptus; it appears to play no significant role in the last two trimesters of pregnancy, because the estrogen and progesterone are then formed by the placenta. Testing for the beta fraction of human chorionic gonadotropin is the basis for most serum and urine pregnancy tests.
Synonym(s): anterior pituitarylike hormone, chorionic gonadotropic hormone, chorionic gonadotrophic hormone.

cho·ri·on·ic go·nad·o·tro·pin

(kōr'ē-on'ik gō-nad'ō-trō'pin)
Glycoprotein with carbohydrate fraction composed of d-galactose and hexosamine, extracted from the urine of pregnant women.
References in periodicals archive ?
Detection of a small molecular species of human chorionic gonadotropin in the urine of patients with carcinoma of the cervix and cervical intraepithelial neoplasia: comparison with other assays for human chorionic gonadotropin and its fragments.
Early serum beta-human chorionic gonadotropin in pregnancies after in vitro fertilization: contribution of treatment variables and prediction of long-term pregnancy outcome.
The association between follicular size on human chorionic gonadotropin day and pregnancy rate in clomiphene citrate treated polycystic ovary syndrome patients.
Is earlier administration of human chorionic gonadotropin (hCG) associated with the probability of pregnancy in cycles stimulated with recombinant follicle-stimulating hormone and gonadotropin-releasing hormone (GnRH) antagonists?
First-service pregnancy rate in beef heifers as influenced by human chorionic gonadotropin administration before and/or after breeding, Theriogenol.
Human chorionic gonadotropin exhibits potent inhibition of preterm delivery in a small animal model.
A very low level of maternal gonadotropin has been associated with Triplody (Schmidt et al., 1994) and low chorionic gonadotropin and alpha-fetoprotein have also been reported in Down syndrome and trisomy 18 (Lehavi et al., 2005; Ozturk et al., 1990).
Human chorionic gonadotropin (HCG) is a naturally occurring hormone necessary to sustain pregnancy The bishops said if the beta form of HCG is carried by a tetanus toxoid molecule and injected into a woman, it becomes an antigen that stimulates production of anti-HCG antibodies, which destroy the natural HCG.
FTC explained, "HCG, or human chorionic gonadotropin, is a hormone produced by the human placenta that for decades has been falsely promoted for weight loss."

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