chordoma

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Related to chordomas: chondrosarcomas

chordoma

 [kor-do´mah]
a malignant tumor arising in the axial skeleton from embryonic remains of the notochord.

chor·do·ma

(kōr-dō'mă), [MIM*215400]
A rare neoplasm of skeletal tissue in adults, derived from persistent portions of the notochord; composed of cells arranged in lobules, with abundant myxoid stroma; some cells contain vacuoles that resemble soap bubbles (physaliphorous cells); most frequently in the region of the clivus or lumbar-sacral cord.
[(noto)chord + G. -oma, tumor]

chordoma

/chor·do·ma/ (kor-do´mah) a malignant tumor arising from the embryonic remains of the notochord.

chordoma

[kôrdō′mə] pl. chordomas, chordomata,
a rare tumor that develops from the fetal notochord. It is usually located in the midline, behind the sella; it is slow growing but highly invasive.

chordoma

An encapsulated, locally invasive malignant tumour that arises from the foetal notochord in the sacrococcygeal and sphenooccipital regions.
 
Epidemiology
Predominantly in older (age 50–70) men for sacrococcygeal region and age 20–40 for sphenooccipital chordoma.
 
Management
Surgery, RT.
 
Prognosis
Recurrence is common, often years after adequate therapy.

chor·do·ma

(kōr-dō'mă)
A rare neoplasm of skeletal tissue in adults, derived from persistent portions of the notochord.
[(noto)chord + G. -oma, tumor]

chordoma

A slow-growing tumour of the spine arising from remnants of the primitive NOTOCHORD. Chordomas rarely spread remotely, but can cause severe local damage.

chordoma

a malignant tumor arising from embryonic remains of the notochord.
References in periodicals archive ?
Outcome of clival chordomas after skull base surgeries with mean follow-up of 10 years.
Chondroid chordomas are relatively less aggressive than conventional chordomas while the dedifferentiated chordomas are more aggressive, faster growing and more likely to metastasize.
Microscopically, chordomas consist of nests or cords of physaliphorous cells separated by fibrous tissue septa and mucoid intercellular substance.
We herein report an exceptional case of extra-axial dedifferentiated chordoma confirmed by the expression of brachyury, the first case report of this kind," reported surgical pathologist Dr.
7) Cranial chordomas are most frequent in men than in women 2:1 and may present at any age with mean age at diagnosis being 38 years.
Extraosseous chordoma of the retropharyngeal space.
We present a case of chordoma, causing caudal compression, which was initially presumed to be a metastatic deposit from a renal cell carcinoma on the basis of radiological investigations.
The hospital revealed that the boy, identified only as Tristan, was facing certain death from a chordoma, a rare, malignant brain tumour, which had wrapped around the 4-year-old's brain stem, making it impossible to use normal surgical techniques.
Chordomas are very rare tumors that are thought to originate from the embryologic remnants of the notochord, the nucleus pulposus.
Chordomas are rare, representing approximately only 1%-4% of all primary bone tumors.
Visualization of tumors such as ependymomas, astrocytomas, Schwannomas and chordomas gives insight into the disease process.
The Massachusetts group has also treated 67 patients with chordomas or chondrosarcomas of the base of the skull or cervical spine--a rather rare tumor, Austin-Seymour says.