chondrosarcoma

(redirected from chondrosarcomas)
Also found in: Dictionary, Thesaurus, Encyclopedia.

chondrosarcoma

 [kon″dro-sahr-ko´ma]
a malignant tumor derived from cartilage cells or their precursors.

chon·dro·sar·co·ma

(kon'drō-sar-kō'mă), [MIM*215300]
A malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and older people; most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion.

chondrosarcoma

/chon·dro·sar·co·ma/ (-sar-ko´ma) a malignant tumor derived from cartilage cells or their precursors.
central chondrosarcoma  one within a bone, usually not associated with a mass.

chondrosarcoma

[kon′drōsärkō′mə] pl. chondrosarcomas, chondrosarcomata
Etymology: Gk, chondros + sarx, flesh, oma, tumor
a malignant neoplasm of cartilaginous cells or their precursors that occurs most frequently in long bones, the pelvic girdle, and the scapula. The tumor is a large, smooth, lobulated growth composed of nodules of hyaline cartilage that may show slight to marked calcification. Also called chondroma sarcomatosum. chondrosarcomatous, adj.
enlarge picture
Chondrosarcoma

chondrosarcoma

A malignant mesenchymal tumour caused by the uncontrolled proliferation of chondroblasts. It is the second most common primary malignancy of bone after osteosarcoma and represents 25% of such lesions.

Epidemiology
Arise in the axial and proximal skeleton of adults and older people.

Clinical findings
Often asyptomatic initially; later, pain for months to years, swelling.

Imaging
MRI is the modality of choice; CT, plain films, show destructive, aggressive permeation of diaphysis by tumour.
 
DiffDx
Metastatic carcinoma, enchondroma, chondromyxoid fibroma.

Types
Clear cell, de-differented, extraskeletal mesenchymal, juxtacortical, mesenchymal, myxoid.

Prognosis
Grade 1, 88% 5-year survival; grade 3, 40% 5-year survival.

chon·dro·sar·co·ma

(kon'drō-sahr-kō'mă)
A malignant neoplasm derived from cartilage cells.

chondrosarcoma

A rare malignant tumour of the cartilaginous parts of bone affecting mainly the pelvis, ribs and breastbone (sternum) and causes a slowly expanding swelling. The outlook after surgical removal is usually favourable.

chon·dro·sar·co·ma

(kon'drō-sahr-kō'mă) [MIM*215300]
A malignant neoplasm derived from cartilage cells.

chondrosarcoma

a malignant tumor derived from cartilage cells or their precursors.
References in periodicals archive ?
Chromosome 9 alterations and trisomy 22 in central chondrosarcoma: a cytogenetic and DNA flow cytometric analysis of chondrosarcoma subtypes.
Clear cell chondrosarcoma of bone: a report of 8 cases.
Chondrosarcoma is considered as a common primary bone sarcoma, which is ranked as the third primary bone malignancy One in five cases of bone sarcomas are due to chondrosarcoma, and half of all cases affect the pelvis (1).
It showed bony trabeculae entrapped by lobules of chondrocytes with chondroid matrix exhibiting pleomorphism, hyperchromasia, mitosis, area of myxoid change and necrosis consistent with well-differentiated chondrosarcoma.
Chang, "Malignant degeneration of a lumbar osteochondroma into a chondrosarcoma which mimicked a large retroperitoneal mass," Skeletal Radiology, vol.
A 58-year-old male with multiple enchondromas experienced malignant degeneration of one into a chondrosarcoma of the distal femur.
Prognostic significance of downregulated expression of programmed cell death 5 in chondrosarcoma.
There are no reports of chondrosarcoma in parrots and few descriptions in other bird species, such as ruffed grouse (Bonasa umbellus) (SIEGFRIED, 1983), great egret (Ardea herodius occidentalis and Ardea alba) (SPALDING & WOODARD, 1992; KUBO et al.
Histopathologically, chondrosarcomas are divided into two types: conventional and variant.
Fine needle aspiration cytology of primary extraskeletal myxoid chondrosarcoma.
75% of chest wall chondrosarcomas arise from the costochondral junction between the ribs and sternum as was observed in our case.