chondroprotective

chondroprotective

A specific compound or chemical that delays progressive joint space narrowing characteristic of arthritis and improves the biomechanics of articular joints by protecting chondrocytes.

chondroprotective

agents that retard degradation of articular cartilage and promote chondrocyte metabolism in the treatment of osteoarthritis in dogs and cats. See also pentosan polysulfate, glycosaminoglycan polysulfate.
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On the other hand, chondroprotective agents such as the antioxidants have been found to promote cartilage repair by stimulating anabolic metabolism of chondrocytes and/or inhibiting catabolic processes found in OA (Altman et al.
Pharmacological treatment is based on analgesics, anti-inflammatories, and chondroprotective drugs to relieve pain and improve function.
14] In other words, Mg serves as a chondroprotective element by increasing the cell proliferation, protein expression, and growth factor efficacy.
Anti-inflammatory and chondroprotective activity of (+)-alpha-pinene: structural and enantiomeric selectivity.
NEM also demonstrated improvements in joint pain and function in a yet to be published canine study, as well as displayed a profound chondroprotective effect, Ms.
Veterinarian-prescribed Cosequin and Dasuquin, both FDA-approved, are more expensive, as is Adequan, a chondroprotective drug injected systemically once or twice a week.
The study sample did not include patients who had one of the following diagnoses: rheumatoid arthritis, ankylopoetic spondylitis, psoriatic arthritis or reactive arthropathy, as well as those patients who used any chondroprotective drugs, such as corticosteroids, sulfate polysaccharides, chemically modified tetracyclines, diacetylrhein or glucosamine [18], or who had a history of trauma of the knee in which the prosthesis was implanted, and the patients with general systemic weakness or acute contagious disease.
Hip dysplasia can be managed through balanced nutrition, exercise, chondroprotective supplements and salvage surgery by performing pectineal myectomy, pelvic osteotomy, intertrochantric osteotomy, excision arthroplasty and total hip prosthesis (Raghuvir et al, 2013, Rawson et al, 2005, Vezzoni et al, 2010, Wallace, 1992).
Proteomic analysis of osteoarthritic chondrocyte reveals the hyaluronic acid-regulated proteins involved in chondroprotective effect under oxidative stress.
Concentration of chondroprotective anabolic cytokines is high in PRP compared to whole blood.