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Radiograph of soft-tissue chondroma in general may show an unmineralised soft-tissue mass or a soft-tissue mass with calcification typical of cartilage tumors [7].
These rare, benign soft-tissue lesions must be differentiated from other mineralizing lesions, such as myositis ossificans, and more aggressive lesions such as synovial chondromas and synovial sarcomas.
The main differential diagnosis to be taken into account is chondrosarcoma, which presents a malignant course and can mean a great challenge for the pathologist to be able to differentiate a low-grade chondrosarcoma from a soft tissue chondroma [2,3].
There are a number of similarities between the two previous cases of bladder chondroma (1,2) and the one described here.
In convexity chondroma, removing the dural attachment along with the tumor is recommended.
During this phase, Hoffa's disease causes transformation of fibrocartilaginous tissue and ossification of degenerative IFP tissue (imitating soft tissue chondroma).
Initial differentials included plasmacytoma and chondroma.
The proximal humerus and adjacent soft tissues are the second most likely region in the extremities to contain a neoplastic lesion; the proximal humerus is the third most common long bone (after distal femur and proximal tibia) affected by bone tumor.(3) Sixty percent to 70% of all shoulder tumors occur in the humerus.(5) Cartilaginous lesions of all types (chondroblastoma, enchondroma, periosteal chondroma, chondrosarcoma) have a predilection for the proximal humerus; marrow cell lesions and metastatic carcinoma are the common malignant lesions.(1) Ten percent to 15% of osseous metastases are in the upper extremity,(4) and of these, 50% will occur in the proximal humerus.(2)
Group II includes cartilage-forming tumours such as chondroma, osteochondroma, chondroblastoma, and chondromyxoid fibroma.
GISTs can be a part of a syndrome called Carney's triad (gastric GIST, pulmonary chondroma, and paraganglioma) or neurofibromatosis type 1 (mostly spindle cell GIST) [11].