As the grade rises, the cellularity increases, the extent of chondroid matrix
falls, and the 10-year survival rate decreases.3,5 Most case series have a slight male predominance; the median patient age is about 50 years.
In chondrolipoma, there are mature adipocytes between the mature cartilage regions and in chondroid lipoma, which is often mistaken for chondrolipoma, there are cells like lipoblasts containing multiple vacuoles in the myxohyaline and chondroid matrix
. Chondroid lipoma shows features of both lipoma and hibernoma; it is also known as lipoma of immature fat, lipoma of the embryonic fat, or fetal lipoma (4).
(3) Chondroid matrix
calcifications are described as "ring-and-arcs," which can be seen with enchondromas (Figure 13) and chondroblastomas.
In the Masson's trichrome stain for collagen fibers, the chondroid matrix
and cellular components were detected in the ASC group, although fibrosis and scar formation were shown in the control group (Figures 5(a) and 5(b)).
Within the chondroid lobules, chondrocytes are in lacunae and have a tendency to cluster with large amounts of intervening chondroid matrix
. This clustering arrangement is typical of soft-tissue chondromas and synovial chondromatosis but is not unique to them .
Histopathologic features of the surgical specimen were characterized by predominant chondroid matrix
with marked cellularity, high grade atypia, and high mitotic activity.
This is explained by the fact that the signal intensity on T1- and T2-weighted MRI images in CBT is dependent on the amounts of various components within the lesion, such as chondroid matrix
, cellularity, calcification, hemosiderin, and aneurysmal bone cyst-like areas.
It showed bony trabeculae entrapped by lobules of chondrocytes with chondroid matrix
exhibiting pleomorphism, hyperchromasia, mitosis, area of myxoid change and necrosis consistent with well-differentiated chondrosarcoma.
The material that consisted of several brown tissue fragments measuring together 6,0 x 3,0 x 1,0 cm was sent for pathological examination, which showed morphological features compatible with myoepithelioma, despite the focal presence of chondroid matrix
and occasional ductal structures.
Caption: Figure 2: (A) In the tumour, mature chondrocyte nests are found in a basophilic chondroid matrix
with myxoid loose areas.
Presence of extensive surrounding reactive edema within the marrow and soft tissues, sclerotic margin, and presence of chondroid matrix
are helpful features distinguishing chondroblastoma from GCT.