Primary variants of lipoma can be listed as angiolipoma, myolipoma, fibrolipoma, angiomyolipoma, myelolipoma, chondroid lipoma
, chondrolipoma, fusiform cell, and pleomorphic lipoma.
Lipomas are classified into various subtypes according to histopathological features, including fibrolipoma, myxolipoma, chondroid lipoma
, and myolipoma.
Some variants with atypical features can be of concern like chondroid lipoma which can be confused with myxoid liposarcoma, chondrosarcoma, soft tissue chondroma, myoepithelial lesions.
DISCUSSION: Chondroid lipoma was described as a separate entity in 1993 by Meis and Enzinger.
Identification of C11orf95-MKL2, the resulting fusion oncogene of t(11;16)(q13;p13), is useful in establishing the diagnosis of chondroid lipoma, a benign soft tissue tumor that can be mistaken for a sarcoma, especially myxoid liposarcoma or extraskeletal myxoid chondrosarcoma.
C11orf95-MKL2 is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipoma. Genes Chromosomes Cancer.
Several variants described include angio-lipoma, chondroid lipoma
, myo-lipoma, spindle cell lipoma, pleomorphic lipoma, fibrolipoma, osteolipoma/chondrolipoma, mylelipoma, adenolipoma, perineural lipoma, myxoid lipoma.
A chondrolipoma must be distinguished from a chondroid lipoma
, which is a separate entity.
In conclusion, giant liposarcomas in scapular region are extremely rare; and possible differential diagnosis may be lipoma, lipoblastoma, pleomorphic lipoma, chondroid lipoma
, hibernoma and neurofibroma etc.
Chondroid lipoma is a recently described benign soft tissue tumor with a predilection for subcutaneous tissue, fascia, or skeletal muscle of the proximal extremities.[1,2] Because it is a rare entity, lack of knowledge of this tumor may lead to erroneous diagnoses, such as extraskeletal chondrosarcoma or myxoid liposarcoma.
Fine-needle aspiration biopsy performed on the lesion produced the diagnosis of chondroid lipoma. Based on this diagnosis, the tumor then was excised in a marginal fashion through the pseudocapsule surrounding the tumor.
Lipomas, lipomatosis, angiolipomas, chondroid lipomas
, lipoblastoma, lipobalostomatosis, spindle cell lipoma and pleomorphic lipomas are lesions that can mimic the condition.