Some variants with atypical features can be of concern like chondroid lipoma which can be confused with myxoid liposarcoma, chondrosarcoma, soft tissue chondroma, myoepithelial lesions.
DISCUSSION: Chondroid lipoma was described as a separate entity in 1993 by Meis and Enzinger.
Grossly chondroid lipoma are well-circumscribed, lobulated, may be encapsulated tumors.
Identification of C11orf95-MKL2, the resulting fusion oncogene of t(11;16)(q13;p13), is useful in establishing the diagnosis of chondroid lipoma, a benign soft tissue tumor that can be mistaken for a sarcoma, especially myxoid liposarcoma or extraskeletal myxoid chondrosarcoma.
C11orf95-MKL2 is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipoma.
3;p13) t(3;17)(q21;p13) t(9;17)(q22;p11-12) t(17;17)(p13;q12) Chondroid lipoma t(11;16)(q13;p12-13) Desmoid-type fibromatosis +8, +20 5q21-22 loss (a) Desmoplastic fibroblastoma t(2;11)(q31;q12) t(11;17)(q12;p11.
Several variants described include angio-lipoma, chondroid lipoma
, myo-lipoma, spindle cell lipoma, pleomorphic lipoma, fibrolipoma, osteolipoma/chondrolipoma, mylelipoma, adenolipoma, perineural lipoma, myxoid lipoma.
A chondrolipoma must be distinguished from a chondroid lipoma
, which is a separate entity.
In conclusion, giant liposarcomas in scapular region are extremely rare; and possible differential diagnosis may be lipoma, lipoblastoma, pleomorphic lipoma, chondroid lipoma
, hibernoma and neurofibroma etc.
Chondroid lipoma is a recently described benign soft tissue tumor with a predilection for subcutaneous tissue, fascia, or skeletal muscle of the proximal extremities.
Fine-needle aspiration biopsy performed on the lesion produced the diagnosis of chondroid lipoma.
Lipomas, lipomatosis, angiolipomas, chondroid lipomas
, lipoblastoma, lipobalostomatosis, spindle cell lipoma and pleomorphic lipomas are lesions that can mimic the condition.