chondroid lipoma

chondroid lipoma

A benign, well-circumscribed neoplasm which is most common in the subcutis of women, superficial muscular fascia or skeletal muscle of extremities. Chondroid lipomas may be difficult to diagnose when the chondroid component predominates. 

DiffDx
Chondrosarcoma, myxoid liposarcoma, myxoid chondrosarcoma, soft tissue chondroma.
References in periodicals archive ?
Primary variants of lipoma can be listed as angiolipoma, myolipoma, fibrolipoma, angiomyolipoma, myelolipoma, chondroid lipoma, chondrolipoma, fusiform cell, and pleomorphic lipoma.
Lipomas are classified into various subtypes according to histopathological features, including fibrolipoma, myxolipoma, chondroid lipoma, and myolipoma.
Some variants with atypical features can be of concern like chondroid lipoma which can be confused with myxoid liposarcoma, chondrosarcoma, soft tissue chondroma, myoepithelial lesions.
DISCUSSION: Chondroid lipoma was described as a separate entity in 1993 by Meis and Enzinger.
Identification of C11orf95-MKL2, the resulting fusion oncogene of t(11;16)(q13;p13), is useful in establishing the diagnosis of chondroid lipoma, a benign soft tissue tumor that can be mistaken for a sarcoma, especially myxoid liposarcoma or extraskeletal myxoid chondrosarcoma.
C11orf95-MKL2 is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipoma. Genes Chromosomes Cancer.
Several variants described include angio-lipoma, chondroid lipoma, myo-lipoma, spindle cell lipoma, pleomorphic lipoma, fibrolipoma, osteolipoma/chondrolipoma, mylelipoma, adenolipoma, perineural lipoma, myxoid lipoma.
A chondrolipoma must be distinguished from a chondroid lipoma, which is a separate entity.
In conclusion, giant liposarcomas in scapular region are extremely rare; and possible differential diagnosis may be lipoma, lipoblastoma, pleomorphic lipoma, chondroid lipoma, hibernoma and neurofibroma etc.
Chondroid lipoma is a recently described benign soft tissue tumor with a predilection for subcutaneous tissue, fascia, or skeletal muscle of the proximal extremities.[1,2] Because it is a rare entity, lack of knowledge of this tumor may lead to erroneous diagnoses, such as extraskeletal chondrosarcoma or myxoid liposarcoma.
Fine-needle aspiration biopsy performed on the lesion produced the diagnosis of chondroid lipoma. Based on this diagnosis, the tumor then was excised in a marginal fashion through the pseudocapsule surrounding the tumor.
Lipomas, lipomatosis, angiolipomas, chondroid lipomas, lipoblastoma, lipobalostomatosis, spindle cell lipoma and pleomorphic lipomas are lesions that can mimic the condition.