chondroid lipoma

chondroid lipoma

an uncommon benign fatty neoplasm occurring as a well-circumscribed, yellow, sometimes encapsulated, slowly growing mass under the skin, typically affecting middle-aged adults, usually women, and most often involving the limb girdles or proximal extremities. It is characterized by a lobular growth pattern and is composed of large vacuolated cells resembling lipoblasts.

chondroid lipoma

A benign, well-circumscribed neoplasm which is most common in the subcutis of women, superficial muscular fascia or skeletal muscle of extremities. Chondroid lipomas may be difficult to diagnose when the chondroid component predominates. 

DiffDx
Chondrosarcoma, myxoid liposarcoma, myxoid chondrosarcoma, soft tissue chondroma.
References in periodicals archive ?
Some variants with atypical features can be of concern like chondroid lipoma which can be confused with myxoid liposarcoma, chondrosarcoma, soft tissue chondroma, myoepithelial lesions.
DISCUSSION: Chondroid lipoma was described as a separate entity in 1993 by Meis and Enzinger.
Grossly chondroid lipoma are well-circumscribed, lobulated, may be encapsulated tumors.
Identification of C11orf95-MKL2, the resulting fusion oncogene of t(11;16)(q13;p13), is useful in establishing the diagnosis of chondroid lipoma, a benign soft tissue tumor that can be mistaken for a sarcoma, especially myxoid liposarcoma or extraskeletal myxoid chondrosarcoma.
C11orf95-MKL2 is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipoma.
3;p13) t(3;17)(q21;p13) t(9;17)(q22;p11-12) t(17;17)(p13;q12) Chondroid lipoma t(11;16)(q13;p12-13) Desmoid-type fibromatosis +8, +20 5q21-22 loss (a) Desmoplastic fibroblastoma t(2;11)(q31;q12) t(11;17)(q12;p11.
Several variants described include angio-lipoma, chondroid lipoma, myo-lipoma, spindle cell lipoma, pleomorphic lipoma, fibrolipoma, osteolipoma/chondrolipoma, mylelipoma, adenolipoma, perineural lipoma, myxoid lipoma.
A chondrolipoma must be distinguished from a chondroid lipoma, which is a separate entity.
In conclusion, giant liposarcomas in scapular region are extremely rare; and possible differential diagnosis may be lipoma, lipoblastoma, pleomorphic lipoma, chondroid lipoma, hibernoma and neurofibroma etc.
Chondroid lipoma is a recently described benign soft tissue tumor with a predilection for subcutaneous tissue, fascia, or skeletal muscle of the proximal extremities.
Fine-needle aspiration biopsy performed on the lesion produced the diagnosis of chondroid lipoma.
Lipomas, lipomatosis, angiolipomas, chondroid lipomas, lipoblastoma, lipobalostomatosis, spindle cell lipoma and pleomorphic lipomas are lesions that can mimic the condition.