Radiography of the right knee (Figure 1) revealed significant chondrocalcinosis
. Additional investigations were performed to screen for conditions associated with CPPD disease, which revealed low levels of magnesium (Mg) (0.9 mmol/L) and ionized Mg (0.21 mmol/L; normal range: 0.43-0.61 mmol/L).
A hereditary type of idiopathic articular chondrocalcinosis
. Survey of a pedigree.
As well, it is clinically important to note the patient in this case report also had subtle findings of Chondrocalcinosis
in the menisci of the knees.
Forestier, "Premature enthusiasm for the use of methotrexate for refractory chondrocalcinosis
: comment on the article by Chollet-Janin et al," Arthritis & Rheumatism, vol.
Foldes, "Knee chondrocalcinosis
: an ultrasonographic study of the hyalin cartilage," Clinical Imaging, vol.
Interestingly, some gout patients have chondrocalcinosis
; patients with hyperparathyroidism have an incidence of chondrocalcinosis
X-ray findings of chondrocalcinosis
are frequently seen in these patients.
It is sometimes called calcium pyrophosphate deposition disease, crystal deposition disease, or chondrocalcinosis
Other risk factors of OA are major knee injuries and chondrocalcinosis
the buildup of calcium pyrophosphate dihydrate crystals in the joints.
and hypomagnesemia: clinical and radiological progression.
The disease can also be asymptomatic, and some patients present only with chondrocalcinosis
that appears at adult age (3).
General radiologic features include dense soft tissue tophi, preservation of joint space, bone erosions (Marginal, periarticular overhanging margin sign, intraosseous] normal bone density, periosteal new bone, secondary degenerative joint changes, chondrocalcinosis
and avascular necrosis.