Unusual benign and malignant chondroid tumors of bone: a survey of some mesenchymal cartilage tumors and malignant chondroblastic tumors, including a few multicentric ones, as well as many atypical benign
chondroblastomas and chondromyxoid fibromas.
(3) Chondroid matrix calcifications are described as "ring-and-arcs," which can be seen with enchondromas (Figure 13) and
chondroblastomas. Osteoid matrix is described as "cloud-like," which can be seen in osteosarcomas (Figure 7).
The majority are considered primary lesions; however, up to 30% can be considered secondary tumors arising from
chondroblastomas, osteoblastomas, nonossifying fibromas, and other benign osseous lesions [1].
Our case showed a lytic lesion with sclerotic rims, and it is difficult to differentiate from other benign bone lesions such as bone cyst, aneurysmal bone cyst, benign
chondroblastomas, giant cell tumors, fibrous dysplasia, and nonossifying fibroma; thus, MRI examination was performed.
Most of the cases were for treatment of benign bony conditions such as giant cell tumor, UBC, ABC, enchondromas, and
chondroblastomas. The group noted overall good results with two local recurrences and one deep infection.
Chondroblastomas are, generally, well-circumscribed lesions involving the medullary cavity.
Chondroblastomas may be mistaken for GCTs because of their subarticular location.
Cytokeratin expression in
chondroblastomas. Histopathology.
Other differential diagnoses of patellar lesions include Sinding-Larsen-Johansson disease, bipartite patella, and a variety of rare tumors such as
chondroblastomas, giant cell tumors, osteoid osteomas, and aneurysmal bone cysts but also malignant tumors [20].
Chondroblastomas usually originates from epiphyseal and apophyeal regions of long bones like humerus, tibia or femur.
Some of the more common masses in the calcaneus include lipomas, solitary bone cysts, and
chondroblastomas. Lipomas have characteristic fat signal.
(97,98) DOG1 has also recently been found to be positive in the cellular areas of 100% (9 of 9) of
chondroblastomas and may have utility in diagnosing this lesion.
