During the past 8 years she had been classified as having appendicitis pancreatitis ischemic enteropathy or irritable bowel syndrome and treated with H1-receptor antagonists glucocorticoids cholinoceptor
blocking drugs etc.
Like the nicotinic cholinoceptor
, it is a pentameric structure and modern techniques of genetic engineering (in particular the production of "knock-out" and "knock-in" mice) have been employed to determine the influences of those five protein strands on the properties of the receptors.
and catecholamines: Proposed mechanism of early adverse haemodynamic reactions.
Involvement of cholinoceptors
in cadmium-induced endothelial dysfunction.
Effects of muscarinic toxins MT1 and MT2 from green mamba on different muscarinic cholinoceptors
Other pharmacologic effects include the following: endothelium relaxation mediated by inhibition of 3', 5'-cyclic GMP (guanosine monophosphate) phosphodiesterase; inhibition of age-related loss of muscarinergic cholinoceptors
and a-adrenoceptors; and stimulation of choline uptake in the hippocampus.
Role of medullary cholinoceptors
in baroreflex bradycardia.
Thus, drugs with an affinity for muscarinic cholinoceptors
prolong the latency and reduce the amplitude , whereas drugs reducing the sympathetic input prolong the recovery time .