cholinergic


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cholinergic

 [ko″lin-er´jik]
1. activated or transmitted by acetylcholine; see also cholinergic fibers and cholinergic receptors.
2. an agent that resembles acetylcholine or simulates its action. Called also parasympathomimetic.

cho·lin·er·gic

(kōl'in-er'jik),
Relating to nerve cells or fibers that use acetylcholine as their neurotransmitter. Compare: adrenergic.
[choline + G. ergon, work]

cholinergic

/cho·lin·er·gic/ (ko″lin-er´jik)
1. parasympathomimetic; stimulated, activated, or transmitted by choline (acetylcholine); said of the sympathetic and parasympathetic nerve fibers that liberate acetylcholine at a synapse when a nerve impulse passes.
2. an agent that produces such an effect.

cholinergic

(kō′lə-nûr′jĭk)
adj.
1. Activated by or capable of liberating acetylcholine, especially in the parasympathetic nervous system.
2. Having physiological effects similar to those of acetylcholine: a cholinergic agent or drug.

cho′li·ner′gi·cal·ly adv.

cholinergic

[-ur′jik]
Etymology: Gk, chole + ergon, to work
1 pertaining to nerve fibers that liberate acetylcholine at the myoneural junctions.
2 the tendency to transmit or to be stimulated by or to stimulate the elaboration of acetylcholine. Also called cholinergic stimulant. Compare adrenergic, anticholinergic.

cholinergic

Pharmacology adjective Referring to a parasympathomimetic effect, specifically on cholinergic receptors, evoking acetylcholine release noun A chemical or drug–eg, bethanechol, that stimulates acetylcholine release from parasympathetic nerve endings. See Parasympathetic nervous system. See Cholinergic crisis. Cf Adrenergic.

cho·lin·er·gic

(kōli-nĕrjik)
Relating to nerve cells or fibers that employ acetylcholine as their neurotransmitter.
Compare: adrenergic
[choline + G. ergon, work]

cholinergic

1. Pertaining to nerves that release ACETYLCHOLINE at their endings, including the nerves to the voluntary muscles and all the PARASYMPATHETIC nerves.
2. Having effects similar to those of acetylcholine.

cholinergic

(of nerve fibres) secreting ACETYLCHOLINE as a TRANSMITTER SUBSTANCE; in vertebrates these include motor fibres to STRIATED MUSCLE, parasympathetic fibres to INVOLUNTARY MUSCLE and fibres to sympathetic ganglia from the central nervous system. Compare ADRENERGIC.

Cholinergic

Nerves that are stimulated by acetylcholine.
Mentioned in: Cholinergic Drugs

cholinergic

acetylcholine-secreting nerve endings (e.g. presynaptic autonomic and postsynaptic parasympathetic nerve endings), or an agent mimicking acetylcholine release

cholinergic (kōˈ·l·nerˑ·jik),

adj pertaining to the parasympathetic part of the autonomic nervous system as well as acetylcholine release and its role as a transmitter agent.

cholinergic 

Relates to neurons or nerve fibres in which acetylcholine (ACh) is the neurotransmitter, or have actions similar to those caused by ACh. Cholinergic receptors are of two types: nicotinic receptors, which are situated in striated muscles (e.g. the extraocular muscles) and muscarinic receptors, which are situated in parasympathetically innervated structures (e.g. the iris and ciliary body). See acetylcholine; nicotine; parasympathomimetic drug.

cho·lin·er·gic

(kōli-nĕrjik)
1. Relating to nerve cells or fibers that use acetylcholine as their neurotransmitter.
2. Drug or chemical with physiologic effects similar to those of acetylcholine.
[choline + G. ergon, work]

cholinergic (parasympathomime-tic) (kō´linur´jik),

adj producing or simulating the effects of acetylcholine.
cholinergic blocking agent,
n See agent, blocking, cholinergic.
cholinergic crisis, in myasthenia gravis,
n a medical condition resulting from an administration of too much anticholinesterase, indicated by an immediate increase in muscle weakness, excessive secretion of pulmonary matter, diarrhea, and cramps.

cholinergic

1. parasympathomimetic; activated or transmitted by acetylcholine; said of nerve fibers that liberate acetylcholine at a synapse when a nerve impulse passes, i.e. the parasympathetic fibers.
2. an agent that resembles acetylcholine or simulates its action.

cholinergic blockade
selective inhibition of cholinergic nerve impulses at autonomic ganglionic synapses, postganglionic parasympathetic effectors, or neuromuscular junctions.
cholinergic neurotransmission
that form of neurotransmission which depends on the production of acetylcholine at synapses.
cholinergic receptors
receptor sites on effector organs or at nerve synapses that are stimulated by acetylcholine released by the nerve terminal. There are two types: muscarinic receptors, present primarily on autonomic effector cells, and nicotinic receptors, present primarily on autonomic ganglion cells and on the motor end plates of skeletal muscle.
References in periodicals archive ?
The mammalian prostate has a rich nerve supply composed mainly of the adrenergic sympathetic nerve and the cholinergic parasympathetic nerve.
Therefore, in the present study, we aimed to examine the impact of GBE on inflammation and cholinergic deficits related to CCH.
The drug's action on central muscarinic cholinergic receptors could be responsible for its effect on mood.
In conclusion, this study indicates Kidsolone had no cholinergic or anti-cholinergic effect, nor did it have an effect on tracheal basal tension.
Presence of cholinergic and calcium channel blocking activities explains the traditional use of Hibiscus rosasinensis in constipation and diarrhoea.
Finally difference of contraction force after administration of atropine as muscarinic cholinergic antagonist was seen in both groups.
The second key challenge, he said, is the need for constant exposure to cholinergic neurons that comprise the nucleus basalis of Meynert (NBM) while avoiding exposure to untargeted neuronal populations.
In humans, cholinergic dysfunction is highly associated with disrupted sleep (13) and impaired memory formation (10,14).
Type II Paralysis or Intermediate Syndrome: It follows the intense cholinergic crisis of organophosphorus poisoning and occurs in up 20%-50% of cases depending on the severity of poisoning, its duration, and on the type of organophosphorus compound.
The initial destruction was in an area called the medial septum, which connects to the hippocampus by GABA and cholinergic neurons.
This author proposed four alternative hypotheses to possibly explain the neuropsychological deficits in MG patients: nocturnal respiratory problems, nonspecific immunological processes, increased mental fatigue, and central cholinergic deficit manifestation.
On the other hand, studies have associated the cholinergic input to the perirhinal cortex in object recognition memory (Abe et al.