CHKA

(redirected from choline kinase alpha)

CHKA

A gene on chromosome 11q13.2 that encodes the first enzyme in CDP-choline pathway of phosphatidylcholine synthesis, catalysing the phosphorylation of ethanolamine; it is thought to play a regulatory role in phosphatidylcholine homeostasis.
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IFN-[alpha] stimulation was also associated with the downregulation of AGPAT5, choline kinase alpha (CHKA), and ethanolamine kinase 1 (ETNK1), which play an important role in the synthesis of phosphatidylglycerol, phosphatidylcholine, and phosphatidylethanolamine.