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Related to cholesterol esterase: Cholesteryl esterase
cholesterol esterase/cho·les·ter·ol es·ter·ase/ (kah-les´ter-ol es´ter-ās) acid lipase; an enzyme that catalyzes the hydrolytic cleavage of cholesterol and other sterol esters and triglycerides. Deficiency of the lysosomal enzyme causes the allelic disorders Wolman's disease and cholesteryl ester storage disease.
LIPAA gene on chromosome 10q23.2 that encodes lipase A, the lysosomal acid lipase (i.e., cholesterol ester hydrolase) that catalyses the hydrolysis of cholesteryl esters and triglycerides in lysosomes.
LIPA mutations are linked to CESD and Wolman disease.