Rupture may result in fibrosis, granulation tissue, hemorrhage, and cholesterol cleft
formation or cholesterol granuloma.
formed by cholesterol crystals were diffusely present within the fibrinoid material (Fig.
and multinucleated giant cells may be seen, along with occasional calcifications.
Intravascular cholesterol clefts
as an incidental finding: cholesterol embolism or nots Am J Dermatopathol 2003; 25: 497-9.
On histologic examination of the mass, vacuolated macrophages, fibrosis, and occasional cholesterol clefts
were identified, consistent with a diagnosis of xanthogranulomatosis.
A definite diagnosis depends on documenting cholesterol clefts
in affected organs.
Histologic examination of the maxillary mass showed fragments of tissue lined by respiratory epithelium with a large number of submucosal cholesterol clefts
Focal collections of foamy macrophages and cholesterol clefts
associated with foreign-body giant cells were present beneath areas denuded of lining cells.
Frequent foreign body-type giant cells were seen in association with cholesterol clefts
There were fragments of mature fibrous tissue with numerous cholesterol clefts
, siderophages, and foci of dystrophic calcification.
There were solid and cystic areas, some containing cholesterol clefts
1,2] Histologically, xanthomas appear as sheets of foamy histiocytes interspersed with inflammatory cells and extracellular cholesterol clefts