Or a patient on donepezil or another cholesterase
inhibitor reports an increased frequency of urination because of the drug's effects on the bladder; in response, tolterodine is prescribed.
Abbreviations: HCE1 (CES1)/HCE2 (CES2), human carboxylesterase 1/2 (human cholesterase
1/2); SCN1NSCN1B, sodium channel, vciltage-gated channel protein, type 1 alpha/beta.
The patch formulation may also be helpful when an Alzheimer's patient does not respond to one of the other two cholesterase
inhibitors, donepezil (Aricept) and galantamine (Razadyne), Dr.