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Related to cholestatic: cholestatic hepatitis, cholestatic jaundice, Cholestatic liver disease


Tending to diminish or stop the flow of bile.


Tending to diminish or stop the flow of bile.


, cholestasia (ko?le-sta'sis) (ko?le-sta'zh(e-)a) [ chole- + stasis]
Arrest of the flow of bile. This may be due to intrahepatic causes, obstruction of the bile duct by gallstones, or any process that blocks the bile duct (e.g., cancer). cholestatic (ko?le-stat'ik), adjective

intrahepatic cholestasis of pregnancy

Abbreviation: ICP
A complication of approx. 1% of pregnancies in which elevated levels of pregnancy hormones cause obstruction to bile flow within the liver. Levels of bilirubin rise in the maternal circulation during the second and third trimesters of pregnancy, causing itching, bile staining of urine, and a lighter stool color than normal. ICP increases the risk of preterm delivery of the fetus and of bleeding disorders and loss of life of the fetus. Synonym: obstetric cholestasis

obstetric cholestasis

Intrahepatic cholestasis of pregnancy.

progressive familial intrahepatic cholestasis

Byler disease.


Tending to diminish or stop the flow of bile.
References in periodicals archive ?
Title: Impact of NGM282 on the Incidence and Severity of Pruritus in Primary Biliary Cirrhosis Patients and Correlations with Liver Chemistries and Serum Bile Acids (Poster 627)Session: Poster Session I - PBC/PSC and Other Cholestatic Disease, Exhibition HallPresenter: Marlyn Mayo, M.
Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited.
Hepatic dysfunction including increased liver enzymes (Elevated AST, ALT, GGT, AP, LDH and bilirubin), and hepatocellular and/or cholestatic hepatitis, with or without jaundice, has been infrequently reported with clarithromycin.
Recently, we performed bile duct ligation on cholestatic Wistar rats and evaluated the degree of liver dysfunction (fibrosis).
Cholestatic hepatitis, cutaneous vasculitis, and vascular deposits of immunglobulin M and complement associated with hepatitis A virus infection.
LpX is often present in association with PBC and cholestatic liver disease.
After excluding right ventricular failure, biliary obstruction, superin fection, and hepatocellular carcinoma, the marked cholestatic jaundice was thought to be caused by thyrotoxicosis.
One or more of these mechanisms could possibly explain QpE cholestatic hepatotoxicity.
The findings support the results of previous small, retrospective case series that also suggested that SSRIs may improve pruritus, which often is the most debilitating symptom of cholestatic liver disease, said Dr.
They include nausea, dizziness, fatigue, shortness of breath, skin rash, nervousness, toxic hepatitis, cholestatic jaundice, nephrotoxicity, and psychosis, particularly with prolonged therapy.