We presented a challenging diagnosis of AMS in an adult patient with severe cholestatic
hepatitis, requiring a large number of investigations to exclude multiple differential diagnoses.
jaundice induced by Epstein-Barr virus infection in the elderly.
One of their patients, originally admitted with acute cholestatic
hepatitis and later diagnosed with FMF, was phenotypically similar to our patient in this case report.
Intake of indigenous medication was found to be associated with adverse outcome and it was associated with development of cholestatic
Studies have shown that clozapine can cause acute necrotic hepatitis, cholestatic
hepatitis with necrosis of a single hepatocyte, and eosinophil infiltration; risperidone usually results in cholestatic
hepatitis and rare allergic symptoms; olanzapine induces hepatocyte damage, accompanied monocytes, centrolobular necrosis of lymphocytes, and eosinophils infiltration in the portal area; quetiapine is the leading cause of hepatocyte damage, extensive necrosis of hepatocytes, and nonspecific inflammatory infiltration; ziprasidone usually causes hepatocyte damage, hypersensitivity, eosinophilic and systemic symptoms drug-induced reaction syndrome; aripiprazole, paliperidone, aripiprazole, amisulpride have no relevant reports.
The BDL model is widely used in experimental studies of cholestatic
Jaundice as a Paraneoplastic Manifestation of Prostate Adenocarcinoma," Clinical Gastroenterology and Hepatology, vol.
Use of everolimus in this post-liver transplant patient led to elevations in AST, ALT, and ALP consistent with mixed hepatocellular and cholestatic
liver injury over a period of three months.
Stanozolol and testosterone propionate are part of the 17 alpha-alkylated (17aa) steroids that have been associated with cholestatic
jaundice usually resolving after drug discontinuation .
A combination of laboratory tests was used to confirm drug-induced liver injury (hepatocellular, cholestatic
, or mixed type) in 9 studies (50.0%), while either AST or ALT was used to confirm the same in 6 studies (33.3%), as shown in Table 2 (see supplement 2 and Table 1 for details).
A core needle biopsy of the liver was performed, which revealed inflammatory activity and apoptotic bodies spanning all zones of the liver, in keeping with acute cholestatic
hepatitis, a pathological picture often related to drug-induced liver injury or nonhepatic viral infection (Figures 1 and 2).
jaundice is an unusual presentation for UTI.