the cholera enterotoxin; an extremely potent protein molecule elaborated by strains of Vibrio cholerae in the small intestine after ingestion of feces-contaminated water and food, where it acts on the epithelial cells to cause hypersecretion of chloride and bicarbonate and an outpouring of large quantities of isotonic fluid from the mucosal surface.
The exotoxin produced during growth in vitro of Cholera vibrio and responsible for the diarrhea seen in association with this infection.
[cholera + G. -gen, producing]
choleragen/chol·er·a·gen/ (kol´er-ah-jen) the exotoxin produced by the cholera vibrio, thought to stimulate electrolyte and water secretion into the small intestine.
an exotoxin produced by the cholera vibrio that stimulates the secretion of electrolytes and water into the small intestine in Asiatic cholera, causing diarrhea and the loss of body fluids and weakening the patient.