The syndrome is characterized by brachycephaly, craniosynostosis, midface hypoplasia, hypertelorism, choanal stenosis
, multidigit hand and foot syndactyly.
Bensimon, "Choanal stenosis: a rare complication of radiotherapy for nasopharyngeal carcinoma," Cancer/Radiotherapie, vol.
Omar, "Velopharyngeal and choanal stenosis after radiotherapy for nasopharyngeal carcinoma" Auris Nasus Larynx, vol.
In this study, 11 patients had 16 choanal lesions; 9 were choanal atresia (4 patients had bilateral atresia and one had unilateral); and 7 were choanal stenosis
(one patient had bilateral stenosis and five patients had unilateral disease).
Acquired posterior choanal stenosis
and atresia: management of this unusual complication after radiotherapy for nasopharyngeal carcinoma.