chlorpropamide


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chlorpropamide

 [klor-pro´pah-mīd]
an oral sulfonylureahypoglycemic agent useful in treatment of type 2 diabetes mellitus in the adult whose condition is stabilized; it is contraindicated in patients with impairment of renal, thyroid, or hepatic function. Dosage is individually adjusted.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

chlorpropamide

(klôr-prō′pə-mīd′)
n.
A long-acting sulfonylurea drug, C10H13ClN2O3S, used to treat type 2 diabetes.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

chlorpropamide

Endocrinology An oral sulfonylurea hypoglycemic, structurally related to tolbutamide, which ↑ release of insulin from beta islet cells in Pts with type 2 DM
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Stirati, "Chlorpropamide in idiopathic diabetes insipidus," Metabolism, vol.
Chlorpropamide (500 [micro]g/ml, 10 [micro]l) was used as the internal standard for extraction and HPLC analysis.
First generation sulfonylureas, like chlorpropamide, should generally be avoided due to active metabolites and hypoglycemia risk.
While all glucose-lowering agents can cause hypoglycemia, it is most likely to occur with the insulin secretagogues, especially the long-acting sulfonylureas chlorpropamide and glyburide.
Medications currently approved to treat type 2 diabetes, 2010 Mean Maximum daily daily Class Drugs doses doses Biguanide Metformin 850 mg (a) 2 550 mg Sulfonylureas Chlorpropamide 250 mg (b) 500 mg Glibenclamide 5 mg (a) 20 mg Glipizide 5 mg (a) 20 mg Glimepiride 4 mg (b) 8 mg Gliclazide 80 mg (a) 320 mg Gliclazide MR 60 mg (b) 120 mg Meglitinides Nateglinide 60 mg (c) 360 mg Repaglinide 2 mg (c) 12 mg Thiazolidinediones Rosiglitazone 4 mg (a) 8 mg Pioglitazone 30 mg (b) 45 mg a-glucosidase Acarbose 50 mg (c) 300 mg inhibitors Miglitol 25 mg (c) 100 mg DPP-4 inhibitors/ Sitagliptin 100 mg (b) 100 mg gliptines Vildagliptin 50 mg (a) 100 mg Saxaglipnin 5 mg (b) 5 mg Incretine analogues Exenatide 20 mcgr (a) 20 mcgr Liraglutide 1.2 mg (b) 1.8mg (a) Twice a day.
The first-generation sulfonylureas currently available are chlorpropamide (Diabinese), tolazamide (Tolinase), and tolbutamide (Orinase).
The drugs (glimepiride, glipizide, glyburide, metformin and chlorpropamide) had been available through the supermarket chain's $4 prescription program.
Glibenclamide ou chlorpropamide en traitement d'un diabete de type 2 (risque d'hypoglycemie prolongee).
In the non-tumoral causes of SIADH, like head trauma, pneumonia, and chlorpropamide therapy, the plasma and urinary AVID concentrations are generally within normal ranges (16).
Patricia is currently taking hydrochlorothiazide (HCTZ), 12.5 mg qd, and lisinopril, 10 mg qd, for hypertension, chlorpropamide, 250 mg qd, for type 2 diabetes, and aspirin, 160 mg qd, daily.
Chlorpropamide, carbamazepine and clofibrate are similarly used albeit less frequently.