chlorpromazine


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chlorpromazine

 [klor-pro´mah-zēn]
a phenothiazine used in the form of the base or the hydrochloride salt as an antipsychotic agent, antiemetic, and presurgical sedative, and in the treatment of intractable hiccups, acute intermittent porphyria, tetanus, and the manic phase of bipolar disorder. It is also used to treat certain severe behavioral problems in children. Side effects include drowsiness and slight hypotension. In prolonged therapy the patient should be observed for jaundice. Some patients on long-term therapy develop persistent tardive dyskinesia.

chlorpromazine

/chlor·pro·ma·zine/ (-pro´mah-zēn) a phenothiazine used in the form of the base or the hydrochloride salt as an antipsychotic, antiemetic, and presurgical sedative, and in the treatment of intractable hiccups, acute intermittent porphyria, tetanus, the manic phase of bipolar disorder, and severe behavioral problems in children.

chlorpromazine

(klôr-prŏm′ə-zēn′, -prō′mə-)
n.
A phenothiazine drug, C17H19ClN2S, usually given in its hydrochloride form and used chiefly to treat schizophrenia and other psychotic disorders, nausea and vomiting, and intractable hiccups.

chlorproMAZINE

[-prō′məzēn]
a phenothiazine drug used as an antipsychotic and antiemetic.
indications It is prescribed in the treatment of psychotic disorders (mania, schizophrenia), severe nausea and vomiting, and intractable hiccups.
contraindications Parkinson's disease, concurrent administration of central nervous system depressants, liver or renal dysfunction, severe hypotension, or known hypersensitivity to this drug or to other phenothiazine medication prohibits its use.
adverse effects Among the more serious adverse effects are hypotension, alteration in cardiac conduction, liver toxicity, a variety of extrapyramidal reactions, blood dyscrasias, and hypersensitivity reactions.

chlorpromazine

Thorazine® An aliphatic phenothiazine, neuroleptic, antipsychotic, with antiadrenergic, anticholinergic, antiemetic, central antihypertensive activity

chlorpromazine

A drug derived from phenothiazine used as an antipsychotic, a tranquillizer and to prevent vomiting (antiemetic). Historically, chlorpromazine was the first truly effective anti-psychotic drug. A brand name is Largactil.

chlorpromazine

antipsychotic agent (Largactil) with antiadrenergic and anticholinergic actions; shows a wide range of adverse effects (e.g. extrapyramidal symptoms [drug-induced parkinsonism, dystonia, akathisia, tardive dyskinesia], hypotension, altered temperature regulation [hypothermia; hyperthermia], insomnia, agitation, convulsions); also used to control neuropathic and chronic pain states

chlorpromazine

a phenothiazine used as an antipsychotic agent and antiemetic. It has been largely superseded in veterinary work by acetylpromazine. Its principal use was as premedication for anesthesia.
References in periodicals archive ?
Considering we compared different classifications of antipsychotic drugs by converting them to chlorpromazine equivalent, we were unable to discuss the correlations between the classifications of antipsychotic drugs and the different affected patterns of TD.
For chlorpromazine, this side effect is related to the dose and period.
In our opinion, the innovation concerning chlorpromazine was reasonable.
Risk of developing metabolic syndrome is greatest with chlorpromazine, clozapine and olanzapine.
Separate odds ratios were estimated for exposure to these drugs, with highest risks for those patients who were prescribed quetiapine, chlorpromazine, and haloperidol, with adjusted odds ratios of 2.
It was to be marketed at $240 per month, or more than 30 times the cost of chlorpromazine.
The relative risk of weight gain is greatest with clozapine and olanzapine, moderate with risperidone, quetiapine and chlorpromazine and least marked with haloperidol.
No differences were seen between DHE alone and chlorpromazine or lidocaine.
Others on the list are cisapride and domperidone, for digestive conditions, and anti-psychotic medications chlorpromazine, haloperidol and pimozideResearchersintheNetherlands, who studied almost 800 cases of sudden heart death, found the seven drugs were probably to bame for at least 320 of them.
From experiments with cell cultures, they found that both quinacrine (a malaria drug) and chlorpromazine (Thorazine, an antipsychotic agent) showed substantial anti-prion properties at concentrations that were safe in humans.
When I hear voices or see the apparitions I take chlorpromazine and it helps rid my mind of these two disturbances.