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1. an antimalarial and antiprotozoal agent, also used as a lupus erythematosus suppressant.
An antimalarial agent used for the treatment and suppression of Plasmodium vivax, P. malariae, and P. falciparum; available in phosphate and sulfate forms. It does not produce a radical cure because it has no effect on the exoerythrocytic stages; chloroquine-resistant strains of P. falciparum have developed in Southeast Asia, Africa, and South America. It is also used for hepatic amebiasis and for certain skin diseases, for example, lupus erythematosus and lichen planus.
chloroquine/chlo·ro·quine/ (klor´o-kwin) an antiamebic and anti-inflammatory used in the treatment of malaria, giardiasis, extraintestinal amebiasis, lupus erythematosus, and rheumatoid arthritis; used also as the hydrochloride and phosphate salts.
A drug, C18H26ClN3, used usually in its phosphate form to prevent and treat malaria and to treat amebiasis that has spread outside the intestines.
indications It is prescribed in the treatment of malaria, extraintestinal amebiasis, rheumatoid arthritis, discoid lupus erythematosus, scleroderma, pemphigus, and photoallergic reactions.
contraindications Retinal or visual field changes, porphyria, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse reactions are GI disturbances, headache, visual disturbances resulting from retinal damage, and pruritus. It can turn the skin blue/black and/or the urine brown/black, bleach the hair, and cause photosensitivity.
An antimalarial agent used for the treatment and suppression ofPlasmodium vivax, P. malariae, and P. falciparum; available in phosphate and sulfate forms. It is also used for hepatic amebiasis and for certain skin diseases, e.g., lupus erythematosus and lichen planus.
chloroquineA drug used in the treatment of MALARIA, RHEUMATOID ARTHRITIS and lupus erythematosus. In 1993 the clinical effectiveness of chloroquine in Malawi was less than 50 percent and it was replaced by sulfadoxine and pyrimethamine. But ten years late the efficiency had risen again to 99 percent. The drug is on the WHO official list. Brand names are Avoclor and Nivaquine.
An antimalarial drug that was first used in the 1940s, until the first evidence of quinine resistance appeared in the 1960s. It is now ineffective against falciparum malaria almost everywhere. However, because it is inexpensive, it is still the antimalarial drug most widely used in Africa. Native individuals with partial immunity may have better results with chloroquine than a traveler with no previous exposure.
Mentioned in: Malaria
An antimalarial agent used for the treatment and suppression of Plasmodium vivax, P. malariae, and P. falciparum; also used for hepatic amebiasis and some skin diseases.
an antiprotozoal agent, used in the treatment of avian malaria, anaplasmosis and theileriosis in cattle and amebiasis in non-human primates.
the drug has an affinity for melanin and ocular tissues with melanin; causes a drug-induced retinopathy.