Rats were either given PhIP alone, or PhIP in combination with 1% chlorophyllin
in their drinking water for a year, to determine its protective effects.
Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin
One of the most potent inducers was isolated from chlorophyllin
, a semisynthetic water-soluble chlorophyll derivative.
Editor's comments: If you do consume foods containing preservatives such as nitrate or nitrite, taking several grams of vitamin C, about 100 mg of chlorophyllin
, and/or cruciferous vegetable extracts might help neutralize the carcinogenic potential of these foods.
Twenty-one male F344 rats in three gavage groups (N=7 rats each) received five daily doses of 250 microg/kg [(3)H]-aflatoxin B(1) ([(3)H]-AFB(1)) alone, or with 250 mg/kg chlorophyllin
(CHL), or an equimolar amount (300 mg/kg) of Chl.
attenuates IFN-gamma expression in lipopolysaccharide-stimulated murine splenic mononuclear cells via suppressing IL-12 production.
PANAFIL combines the enzymatic debridement activity of papain-urea with the pro-healing properties of its chlorophyllin
PANAFILO (Papain, Urea, Chlorophyllin
Copper Complex Sodium) Spray, from HEALTHPOINT, arrived on the market in February, and the wound healing, debriding and deodorizing product has quickly gained a following.
Solution: Targeted DNA Protection and Repair Nutrient Typical Daily Dose Chlorophyllin
100-300 mg Curcumin* 400-800 mg daily Broccoli extract 400-800 mg Watercress extract 50-100 mg Rosemary extract 50-100 mg Apigenin 25-50 mg
The amount of unmetabolized heterocyclic amine excreted in feces was increased by oral administration of chlorophyllin
Bagley was Product Director for two flagship products, ACCUZYME(R) (papain, urea) Ointment/SE and PANAFIL(R) (papain, urea, chlorophyllin
copper complex sodium) Ointment/SE.
According to Kensler, the next question is whether chlorophyllin
can reduce the incidence of liver cancer itself.