chlormethiazole

chlormethiazole

Clomethiazole, a sedative and anticonvulsant drug related to vitamin B1 used in the management of the alcohol withdrawal syndrome and especially DELIRIUM TREMENS, in STATUS EPILEPTICUS, in pre-eclampsia and ECLAMPSIA and to sedate patients unfit for general anaesthesia who are having essential surgery under local anaesthesia. A brand name is Heminevrin.
References in periodicals archive ?
During the 1950s and 1960s, a plethora of new psychoactive substances were registered to treat conditions such as anxiety and depression, including antipsychotics such as chlorpromazine, antidepressant (imipramine), and a range of sedative-hypnotics such as ethchlorvynol, chlormethiazole, meprobamate, methaqualone, and glutethimide.
CYP2E1 inhibition by chlormethiazole (Lu et al., 2008; Wang et al., 2009) or diallyl disulfide (Shimada et al., 2006) ameliorated ethanol-induced pathological changes.
Inclusion criteria for participants were 2-fold: a) only clinically healthy males with normal hepatic function test values were included, and b) only those not taking drugs that alter CYP2E1 activity (e.g., acetaminophen, isoniazid, disulfiram, chlormethiazole, or chloroquine) were included (Frye and Branch 2002; Park et al.
We took morphine, diamorphine, cyclozine, codeine, temazepam, nitrezepam, phenobarbitone, sodium amytal dextropropoxyphene, methadone, nalbuphine, pethidine, pentazocine, buphrenorphine, dextromoramide chlormethiazole. The streets are awash with drugs you can have for unhappiness and pain, and we took them all.
A study of the psychometric effects of chlormethiazole in healthy young and elderly subjects.
The Forum warned doctors against doling out the drug chlormethiazole - commonly prescribed - because it could cause respiratory failure when combined with alcohol.