chlorhexidine

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Related to chlorhexidine digluconate: Chlorhexidine gluconate

chlorhexidine

 [klor-hek´sĭ-dēn]
an antibacterial compound used in antimicrobial skin cleansers for surgical scrub, preoperative skin preparation, and cleansing skin wounds.

chlorhexidine

A disinfectant agent widely used in surgery for preoperative skin cleansing and for sterilizing instruments by soakage. The drug is on the WHO official list. A brand name is Hibitane.

antiseptic 

An agent that kills or prevents the growth of bacteria. This term is generally restricted to agents that are sufficiently non-toxic for superficial application to living tissues. These include the preservatives for eye drops and contact lens solutions. Examples of antiseptics are alcohol, benzalkonium chloride, cetrimide, chlorbutanol, chlorhexidine, hydrogen peroxide, thimerosal (or thiomersalate). Other agents that are too toxic to be applied to living tissues are called disinfectants and are used to sterilize instruments and apparatus. See disinfection; ethylenediamine tetraacetic acid; neutralization; sterilization.

chlor·hex·i·dine

(klōr-heksi-dēn)
A bis-biguanide useful as a topical antiseptic. The gluconate form is used as an oral rinse to inhibit oral bacteria in some conditions.
References in periodicals archive ?
Namely, only povidone-iodine, potassium permanganate, ethanol and Chlorhexidine digluconate exhibited high efficacy (>6-[log.sub.10]) against this bacterial species in comparison to the seven agents showing this maximal activity to S.
Gauze containing 20 ml 2.7% early (15) chlorhexidine digluconate introduction 0.12% to all oral surfaces or (<48 h) of 10 ml chlorhexidine injected antibiotic into oral cavity, 8-hrly, for since 28 days; power tooth brushing randomisation 8-hrly Scannapieco et Chlorhexidine 0.12% solution 16.57% al.
Quality-specific taste impairment following the application of chlorhexidine digluconate mouthrinses.
Chlorhexidine digluconate 0.12% (v/v) (Sigma [R]) was used as positive control for determining MIC and MBC.
Simultaneous immediate and delayed hypersensitivity to chlorhexidine digluconate. Contact Dermatitis 2001; 44:59.
Interaction between chlorhexidine digluconate and sodium lauryl sulfate in vivo.
Taro UK has also been granted a marketing authorization by the Medicines and Healthcare Products Regulatory Agency for Tarodent 0.2% Mouthwash, 0.2% w/v chlorhexidine digluconate (Tarodent Mouthwash).
Two daily rinses with 10 ml of a 0.2% aqueous solution of chlorhexidine digluconate almost completely inhibited the development of plaque, calculus and gingivitis in the human model for experimental gingivitis.
Chlorhexidine digluconate (CHX) at the concentrations of 0.12% and 0.2% is currently used in the treatment of dental and oral mucosal disorders.
Representative standard formulations of oral rinses are supplemented with chlorhexidine digluconate, ethanol, essential oils, and detergents [7, 8].