chlorhexidine


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.

chlorhexidine

 [klor-hek´sĭ-dēn]
an antibacterial compound used in antimicrobial skin cleansers for surgical scrub, preoperative skin preparation, and cleansing skin wounds.

chlorhexidine

/chlor·hex·i·dine/ (klor-heks´ĭ-dēn) an antibacterial effective against a wide variety of gram-negative and gram-positive organisms; used also as the acetate ester, as a preservative for eyedrops, and as the gluconate or hydrochloride salt, as a topical anti-infective.

chlorhexidine

[-hek′sidēn]
an antimicrobial agent used as a surgical scrub, hand rinse, and topical antiseptic. It is effective against gram-positive organisms, gram-negative organisms, aerobes, facultative anaerobes, and yeast.

chlorhexidine

A disinfectant agent widely used in surgery for preoperative skin cleansing and for sterilizing instruments by soakage. The drug is on the WHO official list. A brand name is Hibitane.

chlorhexidine

; Savlon; Hydrex 0.05% chlorhexidine (acetate or gluconate) in industrial methylated spirit (IMS) or water; powerful topical antiseptic effective against a wide range of skin flora, but non-effective against mycobacteria, Pseudomonas or spore forms; incompatible with soap; used for skin cleansing (allow to evaporate to dry for 5 minutes after application); 4% chlorhexidine gluconate in solution (Hibitane) is used as a preoperative surgical scrub

antiseptic 

An agent that kills or prevents the growth of bacteria. This term is generally restricted to agents that are sufficiently non-toxic for superficial application to living tissues. These include the preservatives for eye drops and contact lens solutions. Examples of antiseptics are alcohol, benzalkonium chloride, cetrimide, chlorbutanol, chlorhexidine, hydrogen peroxide, thimerosal (or thiomersalate). Other agents that are too toxic to be applied to living tissues are called disinfectants and are used to sterilize instruments and apparatus. See disinfection; ethylenediamine tetraacetic acid; neutralization; sterilization.

chlor·hex·i·dine

(klōr-heksi-dēn)
A bis-biguanide useful as a topical antiseptic. The gluconate form is used as an oral rinse to inhibit oral bacteria in some conditions.

chlorhexidine (CHX) gluconate,

n brand names: Peridex, PerioGard;
drug class: antiinfective oral rinse;
action: absorbed by tooth surfaces, dental plaque, and oral mucosa; sustained reduction of plaque organisms;
uses: as a rinse as a part of treatment of periodontal disease, irrigation during periodontal procedures, and possibly as an aseptic prerinse before dental procedures.

chlorhexidine

a bisbiguanide antiseptic with antibacterial, antifungal and some antiviral activity; used in skin cleansers for surgical scrub, preoperative skin preparation, cleansing skin wounds and teat dips. Used as the acetate, gluconate or hydrochloride salts. Proprietary names are Hibitane, Nolvasan.

chlorhexidine digluconate
used as a sclerosing agent for chemical vasectomy in dogs.
chlorhexidine teat dip
0.5 to 1.0% chlorhexidine in polyvinylpyrrolidone or as 0.3% solution in water.
References in periodicals archive ?
In the response, a statement was made that, "For patients who may be allergic to iodine compounds, chlorhexidine solutions have been shown to be exceptionally bactericidal.
Chlorhexidine solutions are often used for hand hygiene in hospital settings because hand washing with chlorhexidine solutions has been shown to reduce skin flora by 86% to 92%.
Among infants born to women with group B streptococcus, vertical transmission was found in 54% of those in the chlorhexidine group and 55% of those in the control group.
Chlorhexidine is beneficial as part of a comprehensive protocol for urinary catheterization (35-38).
Chlorhexidine has very low systemic toxic activity in humans and has not produced any appreciable resistance to oral microorganism and has not been associated with any teratogenic alterations.
Chlorhexidine (CHX) was introduced in the 1970s as a topical antimicrobial.
mutans count in plaque were seen in both the green tea and chlorhexidine groups.
Although exposure to chlorhexidine is common, allergic contact dermatitis is rare (Tahoka & Nixon, 2013).
Based on products the surface disinfectant market is segmented into hypochlorite, quaternary ammonium compounds, hydrogen peroxide, chlorhexidine gluconate, peracetic acid, chlorine dioxide, phenolic compounds, alcohols, iodine compounds and aldehydes.
21-23) Saltzman and colleagues cultured the skin immediately after skin preparation and found the culture positive rate to be much lower with chlorhexidine (7%) compared to povidone-iodine scrub (31%); however, neither agent proved to be more effective over the other in regards to elimination of P.
Both chlorhexidine laurate and chlorhexidine palmitate were investigated as the chlorhexidine source.
In the comparison between groups of chlorhexidine mouthwash, chlorhexidine gel and LSO toothpaste at the end of a 5 day period, MS matter measured in the chlorhexidine gel group was significantly lower (*** p < 0.