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an antibacterial compound used in antimicrobial skin cleansers for surgical scrub, preoperative skin preparation, and cleansing skin wounds.


A disinfectant agent widely used in surgery for preoperative skin cleansing and for sterilizing instruments by soakage. The drug is on the WHO official list. A brand name is Hibitane.


An agent that kills or prevents the growth of bacteria. This term is generally restricted to agents that are sufficiently non-toxic for superficial application to living tissues. These include the preservatives for eye drops and contact lens solutions. Examples of antiseptics are alcohol, benzalkonium chloride, cetrimide, chlorbutanol, chlorhexidine, hydrogen peroxide, thimerosal (or thiomersalate). Other agents that are too toxic to be applied to living tissues are called disinfectants and are used to sterilize instruments and apparatus. See disinfection; ethylenediamine tetraacetic acid; neutralization; sterilization.


A bis-biguanide useful as a topical antiseptic. The gluconate form is used as an oral rinse to inhibit oral bacteria in some conditions.
References in periodicals archive ?
Notably, many patients allergic to chlorhexidine report previous mild allergic reactions occurring after exposure in the health care setting.
Kusari also cautions that there is no consensus regarding preprocedure skin sterilization with common products such as Chlorhexidine gluconate 0.5% or povidone iodine, as each can have risks (for example, irritation, thyroid suppression).
A significant difference was observed when black (aq) was compared with oolong (aq) (p value<0.0001) and with chlorhexidine (p value <0.0001).While on comparing oolong (aq) with black (aq), black (alc), oolong (alc) & chlorhexidine respectively a significant difference (p value <0.0001) was obtained.
Effectiveness of 2% chlorhexidine gel and calcium hydroxide against Enterococcus faecalis in bovine root dentine in vitro.
Keywords: Clean contaminated cases, Chlorhexidine alcohol, Povidone iodine, Surgical site infection.
Comparative evaluation of mixture of calcium hydroxide and chlorehexidine with triple antibiotic paste and combination of calcium hydroxide, chlorhexidine and lycopene on incidence of interappointment flare-up: An in vivo study.
Solutions containing chlorhexidine are highly antimicrobial, acting approximately 15 s after application against a wide spectrum of gram-positive and gram-negative bacteria.
The mouthwashes contain several active ingredients, such as chlorhexidine gluconate, phenol mixture with essential oil, povidone-iodine, and hyaluronic acid.
Chlorhexidine Gluconate (CHG) is frequently used to prevent CRBSIs; CHG in the soap used to bathe patients may reduce CRBSIs.
Some authorities recommend skin preparation with chlorhexidine rather than povidone-iodine prior to cesarean delivery.
Similarly, Reza and Khazaei9 have reviewed and performed a meta-analysis to determine the efficacy of 0.2% chlorhexidine bio adhesive gel for prevention of AO incidence after extraction of lower third molar.
Chlorhexidine is today's standard for proper cord care