chloral hydrate


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chloral

 [klor´al]
1. an oily liquid with a pungent, irritating odor; used in the manufacture of chloral hydrate and DDT.
chloral hydrate a sedative and hypnotic used primarily as an adjunct to anesthesia and for sedation of children before certain medical or dental procedures. It is now rarely used for management of insomnia. The Health Care Financing Administration (HCFA) guidelines for long-term care facilities discourages the use of chloral hydrate. The National Institutes of Health Consensus Conference on the Treatment of Sleep Disorders of Older People noted that hypnotic medications such as this should not be the mainstay of management of most causes of disturbed sleep.

chlo·ral hy·drate

a hypnotic and sedative; it is also used externally as a rubefacient, anesthetic, and antiseptic.

chloral hydrate

n.
A colorless crystalline compound, C2H3Cl3O2, used as a sedative and hypnotic drug and in the manufacture of DDT.

chlo·ral hy·drate

(klōrăl hīdrāt)
Hypnotic and sedative; it is also used externally as a rubefacient, anesthetic, and antiseptic.

chloral hydrate

A bitter substance used in solution as a sedative and hypnotic. The drug is on the WHO official list. A brand name is Welldorm elixir.

chlo·ral hy·drate

(klōrăl hīdrāt)
Hypnotic and sedative; also used externally as a rubefacient, anesthetic, and antiseptic.
References in periodicals archive ?
After assessment of the neurological defect score, rats (n = 4 per group) were killed by overdose of 10% chloral hydrate (4 ml/kg BW, i.p.) and rapidly isolated 1mm3 ischemic hemisphere cortex for the next electron microscopy analysis.
Chloral hydrate is widely used as sole agent to induce anesthesia in equines.
At 4, 8, and 16 weeks after the injection of rAAV2-hGAD65 and/or fibroblasts (TH), the PD rats were sacrificed by deep anesthesia with chloral hydrate, followed by intracardial perfusion with 0.9% saline.
At the end of treatment, rats were intraperitoneally anesthetized with 10% chloral hydrate followed by cannulation of right carotid artery for the measurement of mean arterial blood pressure (MABP) using a multi-channel physiological recorder.
An audit of adverse events in children sedated with chloral hydrate or propofol during imaging studies.
Xylazine hydrochloride 0.5 mg/kg of body weight was administered as a pre-anesthetic and Chloral hydrate 1gm/10 kg of body weight (10% solution) as a general anesthesia, intravenously.
The rats were then anesthetized with chloral hydrate (350 mg/kg body wt., i.p) and placed in stereotaxic frame where they received a injection of 50 [mu]g of LPS in 10 [mu]l into the lateral ventricle.
They were mounted in chloral hydrate solution and identified using standard taxonomic keys (13).
Marilyn, who was addicted to barbiturates, overdosed in 1962 on Nembutal and chloral hydrate. It was estimated she had taken 50 pills.