chloral


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Related to chloral: chloral hydrate

chloral

 [klor´al]
1. an oily liquid with a pungent, irritating odor; used in the manufacture of chloral hydrate and DDT.
chloral hydrate a sedative and hypnotic used primarily as an adjunct to anesthesia and for sedation of children before certain medical or dental procedures. It is now rarely used for management of insomnia. The Health Care Financing Administration (HCFA) guidelines for long-term care facilities discourages the use of chloral hydrate. The National Institutes of Health Consensus Conference on the Treatment of Sleep Disorders of Older People noted that hypnotic medications such as this should not be the mainstay of management of most causes of disturbed sleep.

chlo·ral

(klōr'ăl),
A thin oily liquid with a pungent odor, formed by the action of chlorine gas on alcohol.
Synonym(s): anhydrous chloral
References in periodicals archive ?
Chloral hydrate for emergent pediatric procedural sedation: a new look at an old drug.
Chloral hydrate intoxication in a 3-month-old child: Avoidance of hemodialysis by an immediate determination of trichloroethanol.
The rest three parts contain 0.2, 0.4, and 0.6 g of chloral hydrate with 2 ml from the stock 4PNPAN solution.
At the end of 21 days treatment period, all of the animals were decapitated under high dose chloral hydrate anesthesia, 12-14 hours after the last injection; and the brain tissue was quickly taken out of the cranium.
The animals were anesthetized for all procedures with an intraperitoneal injection of chloral hydrate.
Infarct volume was examined 48 h after MCAO; the rats were anesthetized with chloral hydrate (10%, stored in 4[degrees]C refrigerator) and decapitated.
During the MRI imaging scanning, rats were maintained well anesthetized after the use of 5% chloral hydrate with the prone position.
After assessment of the neurological defect score, rats (n = 4 per group) were killed using overdose of 10% of chloral hydrate (4ml/kg BW, i.p.) for the isolation of the brains to measure cerebral infarct volumes using TTC (2, 3, 5-triphenyltetrazolium chloride) staining as previously described by us [24].
Rats were exposed to 10% chloral hydrate (300 mg/kg, ip) to induce anesthesia followed by immobilization in a digital stereotaxic instrument (Stoelting, USA).
Under 10% chloral hydrate anesthesia, rats were irradiated in brain hemisphere (right side: n = 6; left side: n = 6) with a highly collimated 6 MV photon beam from a linear accelerator (Primus-M, Siemens, Germany) with a single dose of approximately 30 Gy.
The lower and upper epidermal layer of fresh leaf (in fragments) were mounted in chloral hydrate and observed under a microscope.
In the case of generalized convulsions lasting more than 30 min, 3% chloral hydrate (2 mL/kg body weight, i.p.; Sigma-Aldrich, St.