CHKB

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CHKB

A gene on chromosome 22q13.33 that encodes a choline kinase-like protein of the choline/ethanolamine kinase family; its exact function is not known.
References in periodicals archive ?
By comparing the results, there is obviously a slight difference in the compressive strength performance, which is produced from this study, CHKL Specification [9], and Zoorob et al.
Antibodies against [gamma]-[H.sub.2]AX, ATM, p-ATM (Serl981), ATR, p-ATR (Ser428), Chkl, p-Chkl (Ser345), Chk2, p-Chk2 (Thr68), AKT, p-AKT (Ser473), mTOR, p-mTOR (Ser2448), ULK1, p-ULKl (Ser317), Beclin-1, p62, LC3, NOX1, NOX2, NOX4, NOX5, p22, Racl, and GAPDH were purchased from Cell Signaling Technology (Beverly, MA, USA).
But the specific molecular pathways regulate cell cycle of normal zygotes and zygotes with oxidative-stressed damage are unclear, and whether DNA damage in zygotes activates cascade of ATM [right arrow] Chkl [right arrow] Cdc25B/Cdc25C during G2/M to repair the damage depends on our further study.
In this study we evaluated the influence of chelidonine and homochelidonine on the expression and the activation of Chkl and Chk2.
The key regulators in response to DNA damage are ATM and ATR kinases, which activated Chkl and Chk2 [40].
Both Amaryllidaceae alkaloids accumulate cells preferentially at G1 and G2 stages of the cell cycle with increased pi 6 expression and Chkl Ser345 phosphorylation.
It was also reported that tDATS activated mitotic arrest in human prostate cancer cells lacking functional p53 (PC-3 and DU145) in association with activation of checkpoint kinase 1 (Chkl) (Herman-Antosiewicz and Singh 2005; Herman-Antosiewicz et al.
Anandamide inhibits Cdk2 and activates Chkl leading to cell cycle arrest in human breast cancer cells.