chimera

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chimera

 [ki-me´rah]
an organism whose body contains different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially.

chi·me·ra

(kī-mēr'ă, ki-),
1. In experimental embryology, the individual produced by grafting an embryonic part of one animal onto the embryo of another, either of the same or of another species.
2. An organism that has received a transplant of genetically and immunologically different tissue, such as bone marrow.
3. Dizygotic twins that exchange immunologically distinct types of erythrocytes.
4. A protein fusion in which two different proteins are linked through peptide bonds; usually genetically engineered. Chimeric antibodies may have the Fab fragment from one species fused with the Fc fragment from another.
5. Any macromolecule fusion formed by two or more macromolecules from different species or from different genes.
[L. Chimaera, G. Chimaira, mythic monster (lit. a she-goat)]

chimera

/chi·me·ra/ (ki-mir´ah)
1. an organism with different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially.
2. a substance created from proteins or genes of two species, as by genetic engineering.chimer´ic

chimera

also

chimaera

(kī-mîr′ə, kĭ-)
n.
1.
a. An organism, organ, or part consisting of two or more tissues of different genetic composition, produced as a result of organ transplant, grafting, or genetic engineering.
b. A gene or protein consisting of parts from two different genes or proteins that are normally distinct, sometimes derived from two different species.
2. An individual who has received a transplant of genetically and immunologically different tissue.

chimera

[kimir′ə, kīmir′ə]
Etymology: Gk, khimaros, fire-breathing monster
an organism carrying cell populations derived from two or more different zygotes of the same or different species. Chimeras include recipients of tissue grafts from other individuals. Compare mosaic.

chimera

Any individual organism or molecule derived from 2 or more species.
 
Embryology
An organism that results when an embryonic part of one organism is grafted onto another.

Genetics
An organism with 2 or more cell lines, genotypes or karyotypes descended from at least 2 zygotes. Chimeras are very rare, only occur in twins and result from chorionic vascular anastomoses, transplantations or double fertilisations and subsequent participation of both fertilised meiotic products in one developing embryo; all hermaphrodites should be karyotyped to evaluate possible chimerism.

Molecular biology
(1) An animal formed from two different embryonic sources. In mouse genetics, targeted mutations produced in embryonic stem cells are recovered by breeding chimeric mice, resulting from the mixture of embryonic stem cells with a genetically distinct blastocyst.
(2) A clone containing genomic DNA from nonadjacent genomic segments or cDNA from two different mRNAs.

Transplantation
The term chimera was once used for a person who had received transplanted tissue—e.g., bone marrow surviving in a recipient.

chi·me·ra

(kī-mēr'ă)
1. The individual produced by grafting an embryonic part of one animal onto the embryo of another, either of the same or of another species.
2. An organism that has received a transplant of genetically and immunologically different tissue, such as bone marrow.
3. Dizygotic twins that have immunologically distinct types of erythrocytes.
4. A protein fusion in which two different proteins, usually from different species, are linked through peptide bonds; usually genetically engineered. Chimeric antibodies may have the Fab fragment from one species fused with the Fc fragment from another.
5. Any macromolecule fusion formed by two or more macromolecules from different species or from different genes.
[L. Chimaera, G. Chimaira, mythic monster (lit. a she-goat)]

chimera

An organism that contains a mixture of genetically different cells derived from more than one ZYGOTE. A chimera may, for instance, occur as a result of fertilization by more than one spermatozoon; fusion of two zygotes; an ALLOGENEIC bone marrow graft; cell exchange between dizygotic twin fetuses; or combination of portions of embryos of different species. Compare MOSAICISM. The term derives from the name of a mythical monster with a lion's head, a goat's body, and a serpent's tail.

chimera, chimaera

1. a mythological, fire-spouting monster with a lion's head, goat's body and serpent's tail.
2. an animal whose body contains different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially; i.e. an individual composed of a mixture of genetically different cells.

chimera protein
see fusion protein.
References in periodicals archive ?
He was also superbly right, a fact I've butted my head against in my own attempts to write about Edward Dahlberg and Nathanael West, each of whose chimerical essence finds itself encircled in a wizardly fashion in the pages of Something Said (in the piece on West, written in 1967, Sorrentino even manages to predict the presidency of Ronald Reagan
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It may be reassuring to believe there are cheap and easy things we can do as individuals to stop global warming, or that the answer is to continue chasing a chimerical global agreement on carbon cuts, as in Cancun.
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The moot arranged by Chimerical Sciences Department was aimed at finding ways for decreasing environmental pollution, inviting suggestions for overcoming energy crisis and deciding a future course of action in this regard, the release added.
Through the work of Chretien de Troyes, Heyworth identifies the changing face of the ethos of chivalry, while in the Canterbury Tales he evokes the social tensions and chimerical hybridity informing Chaucer's creative impulse.
Antisemitism is generally thought to derive from chimerical images of Jews, who became the victims of these projections.
Thus is the chimerical basis of the Thai 'economic miracle' fully bared.
Less than a week later, she apparently joined a group of 20 men who absconded 'with the chimerical idea', wrote David Collins, 'of walking to China or of finding in this country a settlement wherein they would be received and entertained without labour'.
In fact, the cult has a name: Confrerie van de Roze Olifant, or Brotherhood of the Pink Elephant, a chimerical creature those afflicted with the DTs are said to behold.