chimera

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chimera

 [ki-me´rah]
an organism whose body contains different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially.

chi·me·ra

(kī-mēr'ă, ki-),
1. In experimental embryology, the individual produced by grafting an embryonic part of one animal onto the embryo of another, either of the same or of another species.
2. An organism that has received a transplant of genetically and immunologically different tissue, such as bone marrow.
3. Dizygotic twins that exchange immunologically distinct types of erythrocytes.
4. A protein fusion in which two different proteins are linked through peptide bonds; usually genetically engineered. Chimeric antibodies may have the Fab fragment from one species fused with the Fc fragment from another.
5. Any macromolecule fusion formed by two or more macromolecules from different species or from different genes.
[L. Chimaera, G. Chimaira, mythic monster (lit. a she-goat)]

chimera

also

chimaera

(kī-mîr′ə, kĭ-)
n.
1.
a. An organism, organ, or part consisting of two or more tissues of different genetic composition, produced as a result of organ transplant, grafting, or genetic engineering.
b. A gene or protein consisting of parts from two different genes or proteins that are normally distinct, sometimes derived from two different species.
2. An individual who has received a transplant of genetically and immunologically different tissue.

chimera

Any individual organism or molecule derived from 2 or more species.
 
Embryology
An organism that results when an embryonic part of one organism is grafted onto another.

Genetics
An organism with 2 or more cell lines, genotypes or karyotypes descended from at least 2 zygotes. Chimeras are very rare, only occur in twins and result from chorionic vascular anastomoses, transplantations or double fertilisations and subsequent participation of both fertilised meiotic products in one developing embryo; all hermaphrodites should be karyotyped to evaluate possible chimerism.

Molecular biology
(1) An animal formed from two different embryonic sources. In mouse genetics, targeted mutations produced in embryonic stem cells are recovered by breeding chimeric mice, resulting from the mixture of embryonic stem cells with a genetically distinct blastocyst.
(2) A clone containing genomic DNA from nonadjacent genomic segments or cDNA from two different mRNAs.

Transplantation
The term chimera was once used for a person who had received transplanted tissue—e.g., bone marrow surviving in a recipient.

chi·me·ra

(kī-mēr'ă)
1. The individual produced by grafting an embryonic part of one animal onto the embryo of another, either of the same or of another species.
2. An organism that has received a transplant of genetically and immunologically different tissue, such as bone marrow.
3. Dizygotic twins that have immunologically distinct types of erythrocytes.
4. A protein fusion in which two different proteins, usually from different species, are linked through peptide bonds; usually genetically engineered. Chimeric antibodies may have the Fab fragment from one species fused with the Fc fragment from another.
5. Any macromolecule fusion formed by two or more macromolecules from different species or from different genes.
[L. Chimaera, G. Chimaira, mythic monster (lit. a she-goat)]

chimera

An organism that contains a mixture of genetically different cells derived from more than one ZYGOTE. A chimera may, for instance, occur as a result of fertilization by more than one spermatozoon; fusion of two zygotes; an ALLOGENEIC bone marrow graft; cell exchange between dizygotic twin fetuses; or combination of portions of embryos of different species. Compare MOSAICISM. The term derives from the name of a mythical monster with a lion's head, a goat's body, and a serpent's tail.
References in periodicals archive ?
(4) The image stuck, though, and imitations of the chimerical Bosch flooded the market.
The intractable issues of post-colonial Africa have frustrated diplomats and development agencies for decades, and the vague and chimerical suggestions of the authors--that a troubled African nation should simply "get its own house in order," for example--are not policy prescriptions likely to cut the Gordian Knot of Africa's manifold governance problems.
And he will embody, to modern fans, that longed-for but seemingly chimerical owner: a hands-on and benevolent leader who refers to team members as "my boys" (185).
a mirage"; the chimerical Burr "expect[ed] that men would follow in any direction he might lead them" (10, 138).
The glittering lights of chimerical islands with such names as avant-garde theater, film noir, rock n' roll, and open marriage may have captivated single people for a period of time, but they were soon adrift again to find the next thrill.
Following the introduction, Vaughn's chapter on "Africa, Transnationalism, and Globalization," points out the chimerical notion of African nationhood, since "the nation, with its arbitrary colonial origins, was largely invented by 'nationalist' modernizers with tenuous connection to the masses." (p.
It pivots between creation and destruction, the past and the present, and the uneasy chimerical points where they collide." ELLEN KANNER
Reeling, Hanne seeks out the inspiration for the author's novel - a tortured, chimerical actor, once a master in the art of Noh theater.
In addition, Kim Jon-un forcefully mobilized his people to participate in the construction project and his chimerical comment that "a skiing wave will hit the country and North Koreans will become happy by skiing at the Masik Pass Ski Park" has resulted in resentment of the people toward him, the publication added.
"This is a far more realistic goal than chimerical demands that India and Pakistan disarm and sign the NPT as non-nuclear weapons states," he said.
Thus, although a true synaptome of the mammalian brain is a chimerical quest, it is possible that in the near future we will be able to construct a "silicon cortex", a computerised machine based on a realistic model of the complete anatomical, physiological and molecular design of the cortical circuit.
Earlier he served in different leadership and functional capacities for Chimerical Inc, El Paso Corp, Tenneco Energy, the Coastal Corporation, Tangram Transmission Corp and Arthur Young.