chimeric


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chi·mer·ic

(kī-mēr'ik),
1. Relating to a chimera. Compare: mosaicism.
2. Composed of parts that are of different origin and are seemingly incompatible.

chimeric

(kī-mĕr′ĭk, -mîr′-)
adj.
1. Relating to or being an organism, part, or molecule that is a chimera: chimeric mice; chimeric proteins.
2. Relating to a monoclonal antibody produced from the cells of a nonhuman organism, usually a mouse, in which a portion of the antibody has been replaced with a human sequence of amino acids. This is done in the laboratory by replacing part of the DNA sequence in the nonhuman cells with a sequence of human DNA.

chi·mer·ic

(kī-mēr'ik)
1. Relating to a chimera.
Compare: chimera (5)
2. Composed of parts that are of different origin and are seemingly incompatible.
References in periodicals archive ?
Ab initio modeling of the synthetic sequence was exploited to produce 3D models of the chimeric protein.
The chimeric, as Locke and Hume make clear in their use of the Pegasus, is a state that leads us from the plane of perception to the plane of imagination, from empiricism to phantasm.
Chimeric genes apparently form as part of a DNA-reshuffling process.
A difference between w4-m and wp-m involves the successful transfer of the chimeric flower trait through crossing.
The company is focused on chimeric antigen receptor and T cell receptor engineered cell therapies.
Chimeric antigen receptor therapeutic candidate uses messenger RNA (mRNA) as the delivery vehicle for a chimeric antigen receptor transfected into freshly isolated peripheral blood mononuclear cells, allowing for rapid manufacture and delivery back to the patient, without the need for a viral component or cell expansion.
The superior chimeric competency of both human and mouse EPS cells is advantageous in applications such as the generation of transgenic animal models and the production of replacement organs.
"Importantly, the superior interspecies chimeric competency of EPS cells makes them especially valuable for studying development, evolution and human organ generation using a host animal species."
In previous studies, murine and chimeric anti-BMP-2 mAb has been used in mice, rat, and rabbit models and confirmed to be effective in promoting bone repair and regeneration through calvaria defect models [17-20].
Recently, chimeric antigen receptor-modified T- (CART-) cell-based therapy, an innovative approach to tumor treatment, was demonstrated to potentially exhibit MHC-independent antitumor effects.
Chimeric antigen receptor T-cell (CAR-T) therapy boosts a patient's own immune cells to fight cancer and can cost hundreds of thousands of dollars, the Associated Press reported.
Contract notice: specific antibody production - antibody sequencing, recombinant molecular and recombinant production, chimeric and humanized antibodies