chimeric


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

chi·mer·ic

(kī-mēr'ik),
1. Relating to a chimera. Compare: mosaicism.
2. Composed of parts that are of different origin and are seemingly incompatible.
Farlex Partner Medical Dictionary © Farlex 2012

chimeric

(kī-mĕr′ĭk, -mîr′-)
adj.
1. Relating to or being an organism, part, or molecule that is a chimera: chimeric mice; chimeric proteins.
2. Relating to a monoclonal antibody produced from the cells of a nonhuman organism, usually a mouse, in which a portion of the antibody has been replaced with a human sequence of amino acids. This is done in the laboratory by replacing part of the DNA sequence in the nonhuman cells with a sequence of human DNA.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

chi·mer·ic

(kī-mēr'ik)
1. Relating to a chimera.
Compare: chimera (5)
2. Composed of parts that are of different origin and are seemingly incompatible.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
Mentioned in ?
References in periodicals archive ?
Ab initio modeling of the synthetic sequence was exploited to produce 3D models of the chimeric protein.
A CssA, CssB and LTB chimeric protein induces protection against Enterotoxigenic Escherichia coli
The chimeric, as Locke and Hume make clear in their use of the Pegasus, is a state that leads us from the plane of perception to the plane of imagination, from empiricism to phantasm.
The Chimeric Element In Perception: A First Exploration
Chimeric genes apparently form as part of a DNA-reshuffling process.
Hybrid gene forms clue to human, ape origins. (Evolution's DNA Fusion)
A difference between w4-m and wp-m involves the successful transfer of the chimeric flower trait through crossing.
Genetic and Agronomic Evaluation of wp-m in Soybean
The company is focused on chimeric antigen receptor and T cell receptor engineered cell therapies.
Kite Plans New Facility to Expand Cell Therapy Production Capabilities
Chimeric antigen receptor therapeutic candidate uses messenger RNA (mRNA) as the delivery vehicle for a chimeric antigen receptor transfected into freshly isolated peripheral blood mononuclear cells, allowing for rapid manufacture and delivery back to the patient, without the need for a viral component or cell expansion.
MaxCyte doses first patient in MCY-M11 US phase I dose-escalation clinical trial
The superior chimeric competency of both human and mouse EPS cells is advantageous in applications such as the generation of transgenic animal models and the production of replacement organs.
Ability of stem cells expanded to regrow any tissue type
"Importantly, the superior interspecies chimeric competency of EPS cells makes them especially valuable for studying development, evolution and human organ generation using a host animal species."
Stem Cells Can Now Regrow Any Tissue Type
In previous studies, murine and chimeric anti-BMP-2 mAb has been used in mice, rat, and rabbit models and confirmed to be effective in promoting bone repair and regeneration through calvaria defect models [17-20].
Collagen Sponge Functionalized with Chimeric Anti-BMP-2 Monoclonal Antibody Mediates Repair of Critical-Size Mandibular Continuity Defects in a Nonhuman Primate Model
Recently, chimeric antigen receptor-modified T- (CART-) cell-based therapy, an innovative approach to tumor treatment, was demonstrated to potentially exhibit MHC-independent antitumor effects.
Chimeric Antigen Receptor-Modified T Cells for Solid Tumors: Challenges and Prospects
Chimeric antigen receptor T-cell (CAR-T) therapy boosts a patient's own immune cells to fight cancer and can cost hundreds of thousands of dollars, the Associated Press reported.
Medicare to Cover CAR-T Therapy for Leukemia, Lymphoma; Chimeric antigen receptor T-cell therapy boosts a patient's own immune cells

Medical browser ?
Full browser ?