chilblain lupus

chil·blain lu·pus

2. lupus pernio that is a manifestation of sarcoidosis.
References in periodicals archive ?
TREX1 has been linked to a spectrum of diseases including SLE, lupus perniosis (Chilblain lupus), and Aicardi-Goutieres syndrome (AGS) [97-100].
Kono et al., "Severe chilblain lupus is associated with heterozygous missense mutations of catalytic amino acids or their adjacent mutations in the exonuclease domains of 3'-repair exonuclease 1," The Journal of Investigative Dermatology, vol.
LE-specific cutaneous involvement includes acute cutaneous LE with its localized and generalized forms, subacute cutaneous LE with its annular and papulosquamous forms, and chronic cutaneous LE including discoid LE, lupus panniculitis, and chilblain lupus. [8] LE-nonspecific skin lesions are morphologically varied and include vasculitis, livedo reticularis, photosensitivity, alopecia, Raynaud's phenomenon, and bullous lesions.
Lupus pernio or chilblain lupus presents with dusky papules and plaques on the nose, toes, and fingers.
We did not see any case of pyoderma gangrenosum, livedo reticularis, chilblain lupus, Degos-like lesion/atrophie blanche, thrombophlebitis, episcleritis, rheumatoid nodules, erythromelalgia, sclerodactaly.
Chilblain lupus erythematosus--a review of literature.
Another indication of this is the recent characterization of a genetic locus associated with familial chilblain lupus that mapped to chromosome 3p.
* Chilblain lupus. Associated with itching, cold, and painful swelling of the extremities and toes.
The differential diagnosis of pernio includes other cold-induced syndromes such as Raynaud's syndrome, cold panniculitis, cold urticaria, livedo reticularis, acrocyanosis, and chilblain lupus. In chilblain lupus (a form of chronic cutaneous lupus), the lesions may be very similar to pernio but the histopathology is consistent with changes of discoid lupus.
The differential diagnosis of pernio includes other cold-in duced syndromes such as Raynaud's syndrome, cold panniculitis, cold urticaria, livedo reticularis, acrocyanosis, and chilblain lupus. In chilblain lupus (a form of chronic cutaneous lupus), the lesions may be very similar to pernio but the histopathology is consistent with changes of discoid lupus.