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Related to chief cell: parietal cell, G cell, enteroendocrine cell, chief cell of stomach
the predominant cell type of a gland.
Etymology: Fr, chef; L, cella, storeroom
1 also called zymogenic cell. Any one of the columnar epithelial cells or the cuboidal epithelial cells that line the gastric glands and secrete pepsinogen and intrinsic factor, which are needed for the digestion and absorption of vitamin B12 and the normal development of red blood cells. Pernicious anemia may be caused by the absence of intrinsic factor.
2 any one of the epithelioid cells with pale-staining cytoplasm and a large nucleus containing a prominent nucleolus. Cords of such cells form the main substance of the pineal body.
3 also called principal cell. Any one of the polyhedral epithelial cells, within the parathyroid glands, which contain pale, clear cytoplasm and a vesicular nucleus.
chief cell(chēf sel)
The predominant cell type of a gland.
1. Any of the cells of the parathyroid gland that secretes the parathyroid hormone.
2. Any of the cells of the gastric glands that secretes pepsinogen.
See also: cell