Collateral angiography can be performed at the diaphragmatic artery, intercostal artery, adrenal artery, or the thoracic artery, besides the routine celiac artery and superior mesenteric arteries, if necessary, and super-selective embolization can be achieved.[14],[15]
Chemotherapeutics targeting different phases of the cell cycle are recommended, and combined use of
chemotherapeutics is preferred.
The liver, also known as the major detoxifying organ in the body, has a crucial part in transforming and clearing chemicals from systemic circulation, which makes it vulnerable to the toxicity caused by
chemotherapeutic agents.
Chemotherapeutics have been used with some success in birds.
Regarding potential health effects of redox modulators on tumours, they are mainly attributed to cancer chemoprevention, direct anticancer action (for comprehensive review, see [23]), cancer sensitisation to conventional
chemotherapeutics, preferentially through MDR suppression/reversal, cancer sensitisation to radio- and photodynamic therapies, and protection of normal host organs/tissues against damage by chemo- and radiotherapy (Figure 2).
The company introduced its PDC platform for the targeted delivery of
chemotherapeutics during its second quarter financial results call in August 2015.
The researchers discovered that several
chemotherapeutics that stop fast growing tumors have the opposite effect on stem cells in the same animal, causing them to divide too rapidly.
Locally Applied
Chemotherapeutics. For implant patients especially those prone to occasional tissue inflammation, an at-home regimen of daily cleansing with
chemotherapeutic agents in the form of rinses, gels, or solutions is extremely essential.
While several targeted
chemotherapeutics have been developed, the use of these drugs is limited to those patients who exhibit the proper cellular profile, such as triple negative or HER2 positive [2-7].
After four decades they still remain among the most commonly prescribed
chemotherapeutics. These include the taxanes (paclitaxel, docetaxel) and the vinca alkaloids (vincristine, vinblastine).
Recent studies indicated that genetic polymorphism in GSTP1 and GSTM1 genes play a role in the efficacy of detoxifying cytotoxins generated by
chemotherapeutics, including cisplatin and platinum agents, such as adriamycin, methotrexate, cisplatin and vincristine.9-13 Our study indicated that GSTP1 Ile105Val polymorphism may influence the chemotherapy efficacy in patients with osteosarcoma, and individuals with GSTP1GG genotype had poor response to chemotherapy and a shorter survival time.
Objective: The expression of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein and its regulation by
chemotherapeutics were analyzed in primary acute leukemic cells.
In the recent years many studies on anthocyanins have revealed their strong antioxidant activity and their possible use as
chemotherapeutics. The finding that sour cherries (Prunus cerasus L) (also called tart cherries) contain high levels of anthocyanins that possess strong antioxidant and anti-inflammatory properties has attracted much attention to this species.
