chemotherapeutic index


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che·mo·ther·a·peu·tic in·dex

the ratio of the minimal effective dose of a chemotherapeutic agent to the maximal tolerated dose. Originally used by Ehrlich to express the relative toxicity of a chemotherapeutic agent to a parasite and to its host.
Farlex Partner Medical Dictionary © Farlex 2012

che·mo·ther·a·peu·tic in·dex

(kē'mō-thār'ă-pyū'tik in'deks)
The ratio of the minimal effective dose of a chemotherapeutic agent to the maximal tolerated dose. Originally used by Ehrlich to express the relative toxicity of a chemotherapeutic agent to a parasite and to its host.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

chemotherapeutic index

The ratio of the toxicity of a drug, expressed as the maximum tolerated dose per kilogram of body weight to the minimal curative dose per kilogram of body weight. This index is used in judging the safety and effectiveness of drugs.
See also: index
Medical Dictionary, © 2009 Farlex and Partners