chemotaxin


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chemotaxin

 [ke″mo-tak´sin]
a substance, e.g., a complement component, that induces chemotaxis.

chemotaxin

/che·mo·tax·in/ (-tak´sin) a substance, e.g., a complement component, that induces chemotaxis.

chemotaxin

(kem?o-tak'sin)
A substance released by bacteria, injured tissue, and white blood cells that stimulates the movement of neutrophils and other white blood cells to the injured area. Complement factors 3a (C3a) and 5a (C5a), cytokines, leukotrienes, prostaglandins, and fragments of fibrin and collagen are common chemotaxins.
See: inflammation

chemotaxin

a substance, e.g. a complement component, that induces chemotaxis.
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Circulating and tissue levels of the neutrophil chemotaxin interleukin-8 are elevated in severe acute alcoholic hepatitis, and tissue levels correlate with neutrophil infiltration.
The role of innate immunity in alcoholic liver disease
Interleukin 8 (IL-8) is a potent neutrophil activator and chemotaxin that is often used as a biological marker of environmentally induced pulmonary inflammation (Kunkel et al.
Src-mediated EGF receptor activation regulates ozone-induced interleukin 8 expression in human bronchial epithelial cells
2002) Epithelial cell-derived human [beta]-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathway.
Antimicrobial peptide defensin: identification of novel isoforms and the characterization of their physiological roles and their significance in the pathogenesis of diseases
The fact that almost all GAS types possess scp gene is a reason to believe that specific cleavage of C5a chemotaxin contributes to the virulence of these streptococci (13).
Group A streptococcus virulence factors genes in north India & their association with emm type in pharyngitis

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