chemotactic factor

chemotactic factor

Chemoattractant, chemotaxin Immunology Any small molecule that acts as a chemical stimulus along a concentration gradient, attracting macrophages and other cells–eg, to a site of inflammation. See Chemotaxis.
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The identification of this previously unknown Schwann cell chemotactic factor has important implications as it may be beneficial in stimulating Schwann cell migration and hence nerve cell regrowth in artificial grafts.
Suppression of polymorphonuclear leucocyte chemotactic factor production in Propionibacterium acnes by subminimal inhibitory concentrations of tetracycline, ampicillin, minocycline, and erythromycin.
Researchers reported that rheumatoid PBMC cultured with CII produced increase amount of chemotactic factor in the majority of RA patients.14-16 Similar findings were recorded by other investigators using a variety of assay systems.17-19 In contrast, another researcher reported that increased T cell responses to CII were present in only a minority of patients with RA.20
Notably, IL-8, also known as neutrophil chemotactic factor, has been repeatedly implicated as a serological marker of disease activity in patients with BD (18, 19, 21-23).
In some contrast to our results, Murdoch and collaborators indicated that Ang-2 may serve as chemotactic factor for monocytes with proangiogenic potential [39].
Rossi, "The receptor activator of nuclear factor (NF)-kappaB ligand (RANKL) is a new chemotactic factor for human monocytes," The FASEB Journal, vol.
IFN-[gamma]-induced neutrophil migration in vivo may be mediated by the release of the neutrophil chemotactic factor from resident macrophages [42].
There is a key function of Transforming Growth Factor Beta 1 in repair of wounds; it is a strong chemotactic factor for fibroblasts and activates them to produce main extracellular matrix components like collagen.
MCP-1 is a member of the CC chemokine family, an important macrophage/monocyte chemotactic factor and MCP-1 and plays an important role in immunity to spinal tuberculosis (17).
TGFB1 is a strong chemotactic factor for fibroblasts and excites them to build main extracellular matrix constituents like collagen.
A series of chemoattractants, chemokines, orchestrate the recruitment of monocytes/macrophages; the chemokine CCL2 (also known as MCP-1) was first discovered as a tumor-derived chemotactic factor which recruits these cells to tumor tissues [39].