Taken together these data suggest that MPNSTs can be chemoresponsive
tumors and that a well-designed adequately powered prospective trial utilizing epirubicin and ifosfamide is warranted to determine the true benefit to chemotherapy for this subtype of sarcoma.
and Hupp, J.T., Real-time multicolor DNA detection with chemoresponsive
diffraction gratings and nanoparticle probes.
These observations suggest that there may be a utero-ovarian feedback control mediated by ERs on the uterus that cross-talk with vaso-neural pathways; the feedback control may mediate estrogen involved in chemoresponsive
pathways of breast cancer.