ABC transporter expression: clues into chemoresistance
of triple negative breast cancers," presented by Rebecca Feldman, Ph.
Glut-1 as a therapeutic target: increased chemoresistance
and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies.
More recently, increasing evidence has indicated that the engagement of TLRs can promote cancer cell growth, induce evasion of immune surveillance, and enhance tumor metastasis and chemoresistance
, or rather, induction of tumor cell apoptosis depending on ligands (Gonzalez-Reyes et al.
BRAF(V600E) inhibitors have led to clinically significant improvements in outcomes for melanoma patients, yet many patients with metastatic melanoma rapidly succumb to the disease due to eventual chemoresistance
, or insensitivity to the drug.
Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance
Epigenetics and chemoresistance
in colorectal cancer: an opportunity for treatment tailoring and novel therapeutic strategies.
Expression of ERCC1, p53, and class III ,8-tubulin do not reveal chemoresistance
in endometrial cancer: results from an immunohistochemical study.
Cytochrome C Oxidase Activity and Chemoresistance
STAT3 is constitutively active in most tumour cells and interestingly, its activation has been associated with chemoresistance
One mechanism by which this opposition, commonly known as chemoresistance
, happens is through the expression of drug transporter pumps in leukemia cells that actively pump out chemotherapeutics, including Daunorubicin.
There is a struggle in oncology over the use of chemosensitivity and chemoresistance
testing: Can these tests produce better outcomes for patients?
Chemoprevention, chemotherapy, and chemoresistance
in colorectal cancer.