chemoresistance

che·mo·re·sis·tance

(kē'mō-rē-zis'tants),
The resistance of bacteria or malignant cells to the inhibiting action of certain chemical substances used in treatment.

chemoresistance

/che·mo·re·sis·tance/ (-re-zis´tans) specific resistance acquired by cells to the action of certain chemicals.

chemoresistance

1 a specific resistance by components of a cell to chemical substances.
2 the resistance of bacteria or a cancer cell to a chemical designed to treat the disorder.

chemoresistance

1. Resistance of cells to the action of a specific therapeutic agent.
2. Resistance of a particular tumor to chemotherapy; treatment refractory.

che·mo·re·sis·tance

(kē'mō-rē-zis'tăns)
The state of being resistant to a chemical.
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References in periodicals archive ?
DelMar has demonstrated that VAL-083's anti-tumor activity is unaffected by common mechanisms of chemoresistance in vitro.
NEDD4-1 may regulate the proliferation, invasion, migration, and chemoresistance of lung ADC cells through the PI3K/Akt pathway, suggesting that it may be regarded as a therapeutic target for the treatment of lung ADC.
15,64] Hypoxia-induced autophagy also imparted chemoresistance in HCC cells.
The poor response to chemotherapy is hypothesized to be due to either chemoresistance commonly seen in neuroendocrine tumors of other sites, or the lack of an appropriately determined regimen.
33 A lower Bax/Bcl-2 ratio is associated with chemoresistance and adverse cytogenetics in AML.
The higher urolithin A concentration mixture was most effective at inhibiting the number and size of colon-cancer stem cells and inhibiting the activity of aldehyde dehydrogenase, a marker of chemoresistance.
This nanoparticle formulation provides new and promising properties, including overcoming the mechanisms of chemoresistance developed by tumour cells that affect the efficacy of chemotherapy agents.
Currently, authors advocate that the recurrence and chemoresistance are the main problems for its treatment.
Dr Gottesman, whose research interests include mechanisms by which cancers become resistant to chemotherapy, reinforced in his keynote address that traditional monolayer cell culture models used to study tumor chemoresistance have proven to be woefully inadequate.
53) Although it remains to be elucidated whether the altered metabolism directly affects carcinogenesis or chemoresistance, it seems likely that metabolism plays an important role in reprogramming cancer cells to the pluripotent state.
Immediate and transient phosphorylation of the heat shock protein 27 initiates chemoresistance in prostate cancer cells.