Sex differences in morphine-induced ventilatory depression reside within the peripheral
chemoreflex loop.
Maternal protein restriction increases respiratory and sympathetic activities and sensitizes peripheral
chemoreflex in male rat offspring.
[17] Slow pranayamic breathing increases baroreflex sensitivity leading to decreased
chemoreflex activation and thus reduces sympathetic reactivity.
Conversely, the
chemoreflex triggered by the changing concentration of C[O.sub.2] has an influence on respiratory variability (changing the breathing rate and depth) in return [23, 24].
Davisson, "Cardiovascular responses to peripheral
chemoreflex activation and comparison of different methods to evaluate baroreflex gain in conscious mice using telemetry," American Journal of Physiology.
It is likely a function of the energy deficit that is greater than strength exercise and, consequently, the greater sympathetic activation and the lower baroreflex sensitivity due to the increase of the metaboreflex and
chemoreflex activities.
Altered nitric oxide mechanism within the paraventricular nucleus contributes to the augmented carotid body
chemoreflex in heart failure.
Diet and exercise improve
chemoreflex sensitivity in patients with metabolic syndrome and obstructive sleep apnea.
Malhotra, "Clinical consequences of altered
chemoreflex control," Respiratory Physiology & Neurobiology, vol.
This amplified
chemoreflex sensitivity causes a baseline elevated sympathetic tone in OSA, which persists during the day even in the absence of hypoxia [68, 69].
The role of peripheral
chemoreflex sensitivity to hypoxia and hypercapnia in the pathogenesis of various pathological conditions has garnered much attention in recent years.
with simultaneous metaboreflex and
chemoreflex activation was conducted on 13 healthy participants randomized into three groups: gruop I had PC activation with isocapnic hypoxia, group II had isometric handgrip exercise in normoxia and group III had metaboreflex activation in exercise during hypoxia [11].