combined modality therapy using chemotherapy and radiotherapy, designed to reduce the need for surgery by maximizing the interaction between the radiation and the therapeutic agent or agents.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


Chemotherapeutics—e.g., 5-FU, cisplatin, etoposide—followed by radiation therapy to treat cancer.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


A treatment plan that combines chemotherapy and radiotherapy.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Neo-adjuvant chemoradiotherapy for locally advanced rectal cancers is associated with high rates of tumor response in terms of downstagging (complete and partial) and is relatively safe with acceptable morbidity.
Therefore, this study believed that the prolonged OS was impacted largely by chemoradiotherapy, because it can clear some clones that were resistant to EGFR-TKIs and directly kill the tumor cells.
Dynamic contrast-enhanced MRI for treatment response assessment in patients with oesophageal cancer receiving neoadjuvant chemoradiotherapy. Radiother Oncol 2016; 120:128-135.
We experienced one case in which a patient underwent whole circumferential ESD for a whole circumferential lesion and in whom additional chemoradiotherapy was considered to be necessary.
Hence, it was decided to provide the patient with neoadjuvant chemoradiotherapy and then restage with a CT scan.
Neoadjuvant chemotherapy followed by concomitant chemoradiotherapy were indicated, but 2 weeks after the beginning of chemotherapy the patient died suddenly.
Objectives: This study set out with the aim of evaluating the effect of conjugated linoleic acid (CLA) supplementation on quality of life in rectal cancer patients undergoing to preoperative chemoradiotherapy.
The intergroup 0116 trial [20] demonstrated the efficacy of postoperative chemoradiotherapy leading to the use of preoperative chemoradiotherapy (CRT) in GC.
states that CT and PET-CT are safe and useful methods in acquiring diagnosis and deciding resectability after neoadjuvant chemoradiotherapy. The rate of resection was 77% and the debulking rate was only 5% after neoadjuvant therapy.
Because he had been suffering from malnutrition and being at risk for aspiration, he was considered as a high-risk candidate for chemotherapy or chemoradiotherapy. As he desired to resume eating as soon as possible at the sacrifice of his larynx, total pharyngolaryngectomy with jejunal autotransplant reconstruction was performed.
Survival of stomach cancer patients is improved by adjuvant chemoradiotherapy. It is now considered as a standard of care in the USA and should be considered in patients at high risk of recurrence who have not received neoadjuvant therapy.
When history of chemoradiotherapy is absent or unavailable, it is best to interpret these distinctive inflammatory changes in the esophagus as reminiscent of "therapy-related" esophagitis.