chemoradiation

chemoradiation

Chemotherapeutics—e.g., 5-FU, cisplatin, etoposide—followed by radiation therapy to treat cancer.

chemoradiation

Chemoradiotherapy Oncology The sequential use of chemotherapeutics–eg, 5-FU, cisplatin, etoposide, then RT, to treat CA
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'To date, we have had steady enrollment in our two Phase 2 trials, and believe that with the additional capital from our recent financing, we will be in the position to complete enrollment of our Phase 2 clinical trial in China for first-line treatment with radiation for newly diagnosed MGMT-unmethylated GBM patients, as well as both arms of our Phase 2 trial with MD Anderson Cancer Center (MDACC) - one for patients with recurrent disease and one for newly diagnosed patients who have undergone chemoradiation with temozolomide, but will now receive VAL-083 as adjuvant therapy,' commented Saiid Zarrabian, president and CEO of DelMar.
Soligenix has already reported positive results from its Phase 2 clinical study using dusquetide in the treatment of oral mucositis in head and neck cancer (HNC) patients undergoing chemoradiation therapy (CRT).
Imfinzi is also being tested following concurrent chemoradiation therapy in limited-stage SCLC in the Phase III ADRIATIC trial.
The drug is also being assessed in limited-stage SCLC after concurrent chemoradiation therapy in a phase three trial, called ADRIATIC.
However, patients with stage IB2 and bulky stage IIA cancers are usually treated with concurrent cisplatin based chemoradiation, which has been demonstrated in randomized trials to yield better outcomes than radiotherapy alone.
For Imfinzi, data showed 57% of lung cancer patients who had not had disease progression following concurrent chemoradiation therapy, and who were taking the drug, were alive at three years compared to 44% with the placebo following concurrent chemoradiation therapy.
Food and Drug Administration (FDA) has approved an expanded label for KEYTRUDA, Merck's anti-PD-1 therapy, as monotherapy for the first-line treatment of patients with stage III non-small cell lung cancer (NSCLC) who are not candidates for surgical resection or definitive chemoradiation, or metastatic NSCLC, and whose tumors express PD-L1 (tumor proportion score [TPS] [greater than or equal to]1%) as determined by an FDA-approved test, with no EGFR or ALK genomic tumor aberrations.
After maximal transurethral resection of bladder tumour (TURBT), they received 4 courses of chemotherapy with mitomycin and 5 fluorouracil, followed by concurrent chemoradiation using same chemotherapy received 50 Grays in 20 fractions.
The SGX942 development program, for which Soligenix was selected, is for treatment of oral mucositis in neck and head cancer patients receiving chemoradiation treatment.
Patients treated prior to 2008 received split course chemoradiation with a dose of 42.00 to 44.20 Gy in 20 fractions followed six weeks later by a further 15.00 Gy in six fractions to the primary tumour if there was > 50% reduction in tumour size on clinical evaluation.
30, 2018 (HealthDay News) -- For older patients with stage I squamous cell carcinoma of the anus, radiation alone is associated with outcomes that do not differ significantly from those of chemoradiation, according to research published in the July issue of Diseases of the Colon & Rectum.