chemoprotectant

chemoprotectant

 
1. providing protection against the toxic effects of chemotherapy agents.
2. an agent that so acts.

chemoprotectant

/che·mo·pro·tec·tant/ (-pro-tek´tant) providing protection, or an agent providing protection, against the toxic effects of chemotherapeutic agents.

chemoprotectant

1 adj, providing protection against the toxic effects of chemotherapy agents.
2 n, an agent that so acts.
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References in periodicals archive ?
Thus, VC-III can serve as a suitable chemoprotectant and increase the therapeutic window of CDDP in cancer patients.
Data collected from this will inform dose and schedule for further development of G1T28-1, either as a bone marrow chemoprotectant or as an antineoplastic agent.
Therapeutic efficacy of aortic administration of N-acetylcysteine as a chemoprotectant against bone marrow toxicity after intracarotid administration of alkylators, with or without glutathione depletion in a rat model.
Sodium thiosulfate has been shown to be a useful chemoprotectant when used in conjunction with cisplatin.
Since broccoli has long been suspected to contain a chemoprotectant, they tested it first.
NOV-002 is a small molecule compound based on a proprietary formulation of oxidized glutathione that acts together with chemotherapy as a chemopotentiator and a chemoprotectant by regulating redox-sensitive cell signaling pathways.
NOV-002, the lead compound currently in Phase 3 development for lung cancer under an SPA and Fast Track, acts together with chemotherapy as a chemopotentiator and a chemoprotectant.
BHA was used as a positive control to prove a chemoprotectant in assorted animal models of specific carcinogenicity (Hocman, 1988; Iverson, 1995; Iverson, 1999).
The reported findings also support the concept that the dual actions of NOV-002 in cancer patients as both a chemopotentiator and a chemoprotectant may reflect similar redox modulation in tumor and myeloid cells that results in opposite proliferative responses.
NOV-002, the lead compound currently in Phase 3 development for lung cancer under a SPA and Fast Track, acts together with chemotherapy as a chemoprotectant and a chemopotentiator.
The research expands on earlier work in which scientists provided a close-up look at how other plant chemicals also act as chemoprotectants by interfering with the flow of other biochemical signals.