chemoprevention


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chem·o·pre·ven·tion

(kē'mō-prē-ven'shŭn),
The use of drugs or other agents to inhibit the development or progression of malignant changes in cells.

chemoprevention

(kē′mō-prĭ-vĕn′shən, kĕm′ō-)
n.
The use of chemical agents, drugs, or food supplements to prevent the development of cancer.

che′mo·pre·ven′tive adj. & n.

chemoprevention

the use of natural, synthetic or biological substances to suppress or prevent a disease such as cancer. Also called chemoprophylaxis.
Nutrition The use of drugs, chemicals, vitamins or other substances in the diet to prevent or decrease the incidence of a disease—e.g., cancer; chemopreventive agents—supported by some ‘soft’ epidemiologic data—are vitamin-rich fruits, bran, other dietary fibers, and cruciferous vegetables
Oncology Intervention with chemical agents before malignancy—invasion—across an epithelial basement membrane develops, to halt or slow carcinogenesis; chemoprevention aims to directly modulate specific steps in carcinogenesis, prevent DNA damage by free radicals, suppress epithelial proliferation, and promote epithelial differentiation

chemoprevention

Nutrition The use of drugs, chemicals, vitamins or other substance in the diet or to prevent or ↓ the incidence of a disease–eg, CA; chemopreventive agents–supported by 'soft' epidemiologic data are vitamins A, C, E, bran, other dietary fibers, and cruciferous vegetables. See Antioxidant, Antioxidant therapy. Cf Chemoprophylaxis, Unproven methods for cancer management.
References in periodicals archive ?
Professor Julie Bauman of the University of Pittsburgh said: "Green chemoprevention requires less money and fewer resources.
This means that we need a broad spectrum of chemoprevention agents or combination of agents.
Moreover, when she informally polled her audience at the outset of her talk, 93% indicated via electronic clicker that they were not comfortable with chemoprevention for breast cancer and didn't commonly use it in appropriately selected patients in their practice.
The ODAC recommended against prostate cancer chemoprevention labelling for 5ARIs (Table 1).
Pharmacological and clinical data for colorectal carcinoma chemoprevention on Mirtoselect standardized bilberry extract, from Indena, were presented recently at the 51st Annual Meeting of the Italian Cancer Society (SIC) in Sesto San Giovanni, Milano.
The results indicate a previously unexplored pathway through which pomegranate juice constituents may contribute to prostate cancer chemoprevention.
group leader of cancer chemoprevention in the Division of Epigenomics and Cancer Risk Factors at the German Cancer Research Center, in Heidelberg, Germany.
Consider chemoprevention: Chemoprevention is the use of natural or synthetic compounds to reduce the risk of cancer or its recurrence.
The NCI Division of Cancer Prevention invites applications that address developmental research in chemoprevention agent development, biomarkers, early detection, and nutrition science, in addition to clinical studies that focus on specific target organs.
What we're finding is that if you don't have some fat in the meal, all these wonderful" compounds are missed, says Steven Clinton, program leader for molecular carcinogenesis and chemoprevention and the Ohio State University Comprehensive Cancer Center in Columbus.
Chemoprevention is the healthy person's version of chemotherapy, a way to treat cancer with drugs in addition to, or instead of, surgery or radiation.
today announced that, under an Inter-institutional Agreement with The Ohio State University, the University of Kentucky Research Foundation has granted the company an option for an exclusive license to a novel Bioadhesive Berry Gel for the chemoprevention and treatment of oral epithelial dysplasia -- the precancerous lesions that develop into oral squamous cell carcinoma (SCC).