CCL11(redirected from chemokine (C-C motif) ligand 11)
CCL11A gene on chromosome 17q21.1-q21.2 that encodes eotaxin-1, a CC-type cytokine, which is characterised by two adjacent cysteines and, as with all cytokines, is involved in immunoregulatory and inflammatory processes. Eotaxin-1/CCL11 binds CCR3, is chemotactic for eosinophils—but not mononuclear cells or neutrophils—and is involved in eosinophilic type inflammatory responses (e.g., atopic dermatitis, allergic rhinitis, asthma and parasitic infections).
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