chemokine


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Related to chemokine: cytokine, interleukin, Chemokine receptor

chemokine

(kē′mō-kīn′, kĕm′ō-)
n.
Any of various cytokines produced in acute and chronic inflammation that mobilize and activate white blood cells.

CCL1

A gene on chromosome 17q12 that encodes a protein structurally related to the CXC subfamily of cytokines, which are characterised by two cysteines separated by a single amino acid. CCL1 is secreted by activated T cells and is chemotactic for monocytes but not neutrophils; it binds to chemokine receptor CCR8.
References in periodicals archive ?
- The report reviews key players involved in C-X-C Chemokine Receptor Type 2 (CDw128b or GRO/MGSA Receptor or High Affinity Interleukin 8 Receptor B or IL8 Receptor Type 2 or CD182 or CXCR2) targeted therapeutics and enlists all their major and minor projects
The researchers first examined two chemokine receptors called Cxcr4a and Cxcr4b.
This study briefly reports the immune expression profiles of the dual chemokine, CCL17, and homeostatic chemokines CCL21, and CCL24 in the large yellow croaker.
White, "Cytokine and chemokine regulation of sensory neuron function," Handbook of Experimental Pharmacology, vol.
This indicates a benefit of having the chemokine adjuvant and antigen expressed in the same transformed cell.
The Duffy blood group antigens, also called Duffy antigen receptor for chemokines (DARC), recently renamed atypical chemokine receptor 1 (ACKR1).
Ablation of phosphodiesterase 4B reduces lipopolysaccharide-induced CC chemokine ligand 3 production in macrophages
HIV-1 and HIV-2 strains have been reported to be capable of utilising several alternative chemokine receptors, including CCR2b, CXCR4, CXCR6 and GPR1, to mediate infection of cells.
ACKR2 is a chemokine decoy receptor [15] which can bind and internalize chemokines without activating an intracellular response [16].
Mogamulizumab is a humanised monoclonal antibody (mAb) that is directed against CC chemokine receptor 4 (CCR4), which is frequently expressed on leukemic cells of certain haematologic malignancies, including CTCL.
Atypical chemokine receptor 1 has become a focus of research because of its diverse roles in different diseases.

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