chemically-modified hemoglobin

chemically-modified hemoglobin

Transfusion medicine A stabilized Hb solution designed to carry O2 or serve as a blood substitute; CMHs remain in the intravascular space for 12 hrs to 4 days and may interfere with measurement of Hb, BR, and lipids, but do not interfere with antibody testing. See Blood substitute, Perfluorocarbon.
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* Chemically-modified hemoglobin can cause interference in HbA1c methods such as ion exchange and electrophoresis which separate hemoglobin species on the basis of charge differences.
* It is free from interference from chemically-modified hemoglobin.

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