chemical modification


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chem·i·cal mod·i·fi·ca·tion

alteration in the structure of a molecule, typically a macromolecule such as a protein, by chemical means; often, the covalent addition by some reagent.
References in periodicals archive ?
Histones, DNA and RNA are the target of sophisticated chemical modification, which establishes a second layer of information.
Several techniques have been used for chemical modification of polymers, fillers, and composites in order to improve specific properties [8-11].
The specific signature results from a chemical modification of DNA called methylation, which can control the expression of genes like a dimmer on a light switch.
When colon, lung, breast, stomach and endometrial cancer is present, a "striking" chemical modification of DNA occurs, said researchers from the National Human Genome Research Institute (NHGRI) in the US.
Prof Uzma presented her project with the help of slides, explaining various stages of drug discovery process and chemical modification of knowndrug.
Compared with living people, Neandertals and ancient Siberians known as Denisovans had slightly different patterns of DNA methylation --a chemical modification of DNA that doesn't change the information in genes but helps control gene activity.
To create his age predictor, UCLA professor of human genetics, Steve Horvath, PhD, ScD, focused on a naturally occurring process called methylation, a chemical modification of one of the four building blocks that make up our DNA.
In addition, a proprietary chemical modification of the chains enhances the rubber/filler interaction, especially with carbon black in sidewall compounds, maintaining the dynamic performance of the tires made with the new grades at the high level of the company's standard NdPBR grades.
Among the topics are the basic concepts and behavior of rubber elasticity, characterizing structure in the science and technology of elastomers, the viscoelastic behavior of rubber and dynamics of blends, the rheological behavior and processing of unvulcanized rubber, vulcanization, reinforcing elastomers by particulate fillers, the science of rubber compounding, the strength of elastomers, the chemical modification of polymers, tire engineering, and recycling rubbers.
Functionalization of nanoparticles is accomplished by either ligand exchange or chemical modification of the terminal functional groups of the capping ligand.
Biosorption potential was enhanced by chemical modification and surface chemistry changes were studied by recording FT-IR spectra of biosorbent.
The researchers tested three genes in a specific type of breast cell that shed in milk for methylation, a chemical modification that can inactivate a gene by disabling its start switch.