chelator


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Related to chelator: chelate compound, EDTA, Chelant

chelator

A chemical–eg, EDTA that binds metal ions from solutions. See Chelation therapy.
References in periodicals archive ?
The pH and ionic strength of solution have remarkable influence on the extent of complexation, which regulates the fraction of the retained metals by the chelator [32].
In order to increase the effects of irrigants and chelators, particularly in the apical portion, laser systems have been used in recent years (7).
The use of this oral chelator DMSA is considered safe for children, but it is not recommended for pregnant or lactating women and patients with kidney disorders.
The iron chelator Dp44mT causes DNA damage and selective inhibition of topoisomerase IIalpha in breast cancer cells.
Several studies have indicated that the metal chelator TPEN induces intracellular zinc depletion in several cell types [5, 33, 34] and here the effects of chelator TPEN on the SHSY5Y neuroblastoma cell viability were assessed using the MTT assay.
In the copper chelation assay, the uses of different concentrations (1, 2, 3, 4, 5, 7mg/ml) of the same extracts or (10, 20, 30, 40, 50, 70 [micro]g/ml) of the EDTA showed a significant (p [less than or equal to] 0.01) dose dependent ability to chelate copper ions with 0,43 [+ or -] 0,03 at 7mg/ml compared to the control and the rest extracts (CLE, EALE and MLE) which presented a high stable absorbance, but this capacity still low compared to the standard chelator which gave a very significant (p [less than or equal to] 0.001) capacity with 0,13 [+ or -] 0,005 at only 70 [micro]g/ml.
The Chelators, organic or inorganic agents are being widely used for metals mobilization to rehabilitate the metal contaminated soils by plants (Madrid et al., 2003; Chen et al., 2014), they form the water soluble complexes with metal ions and desorb them from various soil components (Sun, 2009).
Chelators are classified according to their iron-binding capacities.
Efficacy and safety of deferasirox, an oral iron chelator, in heavily iron-overloaded patients with beta-thalassemia: the ESCALATOR study.
This toxic iron was the constituent bound and deactivated by chelators. So cardiac injury in patients with transfusional iron overload was best prohibited by maintaining the small level of chelator in the blood circulation (Link et al.
Seven of the methods were chelating assays based on 5 different chelators, and one was our BDI assay (2).